Evidence map›Paper›PMID 35521126›Full record

ArticleRSC advances2020

Short peptides conjugated to non-peptidic motifs exhibit antibacterial activity.

Natalia Ardila-Chantré, Angie Katherine Hernández-Cardona, Hector Manuel Pineda-Castañeda, Sandra Mónica Estupiñan-Torres, Aura Lucía Leal-Castro, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Javier Eduardo García-Castañeda

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Natalia Ardila-ChantréDepartamento de Ciencias, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 450, Office 203 Bogotá Zip Code 11321 Colombia jaegarciaca@unal.edu.co.ORCID https://orcid.org/0000-0001-7491-4508
Angie Katherine Hernández-CardonaDepartamento de Bacteriología, Universidad Colegio Mayor de Cundinamarca Bogotá Calle 28 No. 5B-02 Bogotá 110311 Colombia.
Hector Manuel Pineda-CastañedaDepartamento de Ciencias, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 450, Office 203 Bogotá Zip Code 11321 Colombia jaegarciaca@unal.edu.co.ORCID https://orcid.org/0000-0002-9081-0546
Sandra Mónica Estupiñan-TorresDepartamento de Bacteriología, Universidad Colegio Mayor de Cundinamarca Bogotá Calle 28 No. 5B-02 Bogotá 110311 Colombia.
Aura Lucía Leal-CastroFacultad de Medicina, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 471 Bogotá Zip Code 11321 Colombia.
Ricardo Fierro-MedinaDepartamento de Ciencias, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 450, Office 203 Bogotá Zip Code 11321 Colombia jaegarciaca@unal.edu.co.ORCID https://orcid.org/0000-0003-4636-4443
Zuly Jenny Rivera-MonroyDepartamento de Ciencias, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 450, Office 203 Bogotá Zip Code 11321 Colombia jaegarciaca@unal.edu.co.ORCID https://orcid.org/0000-0001-6915-8488
Javier Eduardo García-CastañedaDepartamento de Ciencias, Universidad Nacional de Colombia Carrera 45 No. 26-85, Building 450, Office 203 Bogotá Zip Code 11321 Colombia jaegarciaca@unal.edu.co.ORCID https://orcid.org/0000-0001-6882-4397
Universidad Nacional de Colombia · COUniversidad Colegio Mayor de Cundinamarca · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short peptides derived from buforin and lactoferricin B were conjugated with other antimicrobial molecules of different chemical natures. The sequences RLLR, RLLRLLR, RWQWRWQWR, and RRWQWR were conjugated at their N-terminal end with non-peptidic molecules such as 6-aminohexanoic acid, ferrocene, caffeic acid, ferulic acid, and oxolinic acid. Peptide conjugates and unmodified peptides were synthesized by means of solid-phase peptide synthesis using the Fmoc/

Identifiers

PMID35521126
PMCPMC9055962
OpenAlexW3048445561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.