Evidence map›Paper›PMID 35521039›Full record

ArticleBulletin of the World Health Organization2022

Prospective cohort study of referred Malawian children and their survival by hypoxaemia and hypoglycaemia status.

Carina King, Beatiwel Zadutsa, Lumbani Banda, Everlisto Phiri, Eric D McCollum, Josephine Langton, Nicola Desmond, Shamim Ahmad Qazi, Yasir Bin Nisar, Charles Makwenda and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06176664 (Oxygen Therapy for Children With Moderate Hypoxemia in Malawi), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06176664 nacompletednot on this mapstarted 2024, after this paper: background citation

Oxygen Therapy for Children With Moderate Hypoxemia in Malawi: Pilot Randomized Control Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2024 to 2024Enrolled21ConditionsPneumoniaArmsLow flow oxygen, High-flow nasal cannula oxygen
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carina KingDepartment of Global Public Health, Karolinska Institutet, Tomtebogatan 18a, Stockholm, 17177, Sweden.
Beatiwel ZadutsaParent and Child Health Initiative, Lilongwe, Malawi.
Lumbani BandaParent and Child Health Initiative, Lilongwe, Malawi.
Everlisto PhiriParent and Child Health Initiative, Lilongwe, Malawi.
Eric D McCollumGlobal Program in Respiratory Sciences, Johns Hopkins University, Baltimore, United States of America.
Josephine LangtonDepartment of Paediatrics, College of Medicine, Blantyre, Malawi.
Nicola DesmondBehaviour and Health Group, Malawi-Liverpool-Wellcome Trust Programme, Blantyre, Malawi.
Shamim Ahmad QaziDepartment of Maternal, Newborn, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland.
Yasir Bin NisarDepartment of Maternal, Newborn, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland.
Charles MakwendaParent and Child Health Initiative, Lilongwe, Malawi.
Helena HildenwallDepartment of Global Public Health, Karolinska Institutet, Tomtebogatan 18a, Stockholm, 17177, Sweden.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Objective: To investigate survival in children referred from primary care in Malawi, with a focus on hypoglycaemia and hypoxaemia progression. Methods: The study involved a prospective cohort of children aged 12 years or under referred from primary health-care facilities in Mchinji district, Malawi in 2019 and 2020. Peripheral blood oxygen saturation (SpO Findings: Of 826 children recruited, 784 (94.9%) completed follow-up. At presentation, hypoxaemia was moderate (SpO Conclusion: Presumptive pre-referral glucose treatment and better management of hypoglycaemia could reduce the high case fatality ratio observed in children with severe hypoglycaemia. The morbidity and mortality burden of severe hypoxaemia was high; ways of improving hypoxaemia identification and management are needed.

Indexed as

Blood GlucoseHypoglycemiaChildCohort StudiesHumansHypoxiaProspective StudiesReferral and ConsultationBlood Glucose

Identifiers

PMID35521039
PMCPMC9047421

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.