Evidence map›Paper›PMID 35520789›Full record

ArticleRSC advances2019

Synthesis and characterization of photocrosslinkable hydrogels from bovine skin gelatin.

Sanika Suvarnapathaki, Michelle A Nguyen, Xinchen Wu, Syam P Nukavarapu, Gulden Camci-Unal

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Scaffolds Bioink for Three-Dimensional (3D) Bioprinting.Food science of animal resources · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Engineering metabolism to modulate immunity.Advanced drug delivery reviews · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sanika SuvarnapathakiBiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell One University Avenue Lowell MA 01854 USA.
Michelle A NguyenDepartment of Chemical Engineering, University of Massachusetts Lowell One University Avenue Lowell MA 01854 USA Gulden_CamciUnal@uml.edu.ORCID https://orcid.org/0000-0001-8305-5303
Xinchen WuBiomedical Engineering and Biotechnology Program, University of Massachusetts Lowell One University Avenue Lowell MA 01854 USA.
Syam P NukavarapuDepartment of Biomedical Engineering, University of Connecticut 260 Glenbrook Road, Storrs CT 06269 USA.ORCID https://orcid.org/0000-0003-0852-9489
Gulden Camci-UnalDepartment of Chemical Engineering, University of Massachusetts Lowell One University Avenue Lowell MA 01854 USA Gulden_CamciUnal@uml.edu.ORCID https://orcid.org/0000-0003-4258-844X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels that mimic native tissues chemically and structurally have been increasingly sought for a wide variety of tissue engineering applications. Gelatin can be naturally derived from different sources and functionalized to fabricate hydrogels that exhibit high cytocompatibility and favorable biodegradable properties. The amino groups on the gelatin backbone can be substituted by adding varying proportions of methacrylic anhydride (MAA) to create biomimetic hydrogels which can be used as tissue engineering scaffolds. Gelatin from different sources yields hydrogels with distinctive physical, chemical, and biological properties. In this work, gelatin from bovine skin was used to fabricate hydrogels with varying degrees of crosslinking content using 1, 4, 7, and 10 mL MAA. The material properties of these hydrogels were characterized. The cytocompatibility of the gelatin-based hydrogels was studied using L6 rat myoblasts. The hydrogels from bovine skin gelatin exhibit mechanical properties that are conducive for applications which require substrates to propagate cell growth, migration, and proliferation rapidly. These hydrogels exhibit exceptional tunability behavior which makes them useful and applicable to culture different cell types.

Identifiers

PMID35520789
PMCPMC9063771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.