Evidence map›Paper›PMID 35520685›Full record

ArticleRSC advances2020

Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-β-lactamase inhibitors.

Yu-Hang Yan, Jian Chen, Zhen Zhan, Zhu-Jun Yu, Gen Li, Li Guo, Guo-Bo Li, Yong Wu, Yongxiang Zheng

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Phytotoxicity Study of (Amino)imidazo[1,2-Journal of agricultural and food chemistry · 2025
    Article
  4. Approachable Synthetic Methodologies for Second-GenerationPharmaceuticals (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu-Hang YanKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Jian ChenKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Zhen ZhanKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Zhu-Jun YuKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Gen LiKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Li GuoKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.
Guo-Bo LiKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.ORCID https://orcid.org/0000-0002-4915-6677
Yong WuKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.ORCID https://orcid.org/0000-0003-0719-4963
Yongxiang ZhengKey Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, Sichuan Engineering Laboratory for Plant-Sourced Drug, Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University Sichuan 610041 China yongxiangzheng@scu.edu.cn +86 199 3880 2868.ORCID https://orcid.org/0000-0002-9068-5765

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-Lactam antibiotic resistance mediated by metallo-β-lactamases (MBL) has threatened global public health. There are currently no available inhibitors of MBLs for clinical use. We previously reported the ruthenium-catalyzed meta-selective C-H nitration synthesis method, leading to some

Identifiers

PMID35520685
PMCPMC9056430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.