Evidence map›Paper›PMID 35520620›Full record

ArticleHeliyon2022

Association of toll-like receptors in malaria susceptibility and immunopathogenesis: A meta-analysis.

Aína Danaisa Ramirez Ramirez, Myrela Conceição Santos de Jesus, Júlia Rossit, Nathália Faria Reis, Marcelo Cerilo Santos-Filho, Adriana Pittella Sudré, Joseli de Oliveira-Ferreira, Andrea Regina de Souza Baptista, Luciane Moreno Storti-Melo, Ricardo Luiz Dantas Machado

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aína Danaisa Ramirez RamirezCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Myrela Conceição Santos de JesusCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Júlia RossitCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Nathália Faria ReisCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Marcelo Cerilo Santos-FilhoCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Adriana Pittella SudréLaboratory of Parasites Molecular Biology, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Joseli de Oliveira-FerreiraLaboratory of Immunoparasitology, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil.
Andrea Regina de Souza BaptistaCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Luciane Moreno Storti-MeloLaboratory of Molecular Genetics and Biotechnology, Department of Biology, Center for Biological and Health Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Ricardo Luiz Dantas MachadoCenter for Microorganisms' Investigation, Department of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
Universidade Federal Fluminense · BRUniversidade Federal de Sergipe · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptors (TLRs) play a key role in the induced immune response in malaria. Although the potential roles of TLRs have been described, it is necessary to elucidate which of these receptors may actually have an impact on the immunopathogenesis of the disease. This article performed a meta-analysis adhered to the PRISMA statement on TLRs studied in malaria by

Indexed as

MalariaPlasmodium falciparumPlasmodium vivaxPolymorphismTLRToll-like receptors

Identifiers

PMID35520620
PMCPMC9065626
OpenAlexW4224280260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.