Evidence map›Paper›PMID 35520517›Full record

ArticleRSC advances2019

One step DNA amplification of mammalian cells in picoliter microwell arrays.

Wenwen Liu, Zhao Li, Yuanjie Liu, Qingquan Wei, Yong Liu, Lufeng Ren, Chenyu Wang, Yude Yu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenwen LiuState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.ORCID https://orcid.org/0000-0002-8017-0557
Zhao LiState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Yuanjie LiuState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Qingquan WeiState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Yong LiuState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Lufeng RenState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Chenyu WangState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.ORCID https://orcid.org/0000-0002-0794-427X
Yude YuState Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences P. O. Box 912 Beijing 100083 China yudeyu@semi.ac.cn.
Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed a strategy for direct DNA amplification of single cells on a PEG-modified silica chip with 30 600 picoliter-sized microwells. HPV-positive cells in heterogeneous populations were successfully detected with high accuracy sensitivity as high as single copy.

Identifiers

PMID35520517
PMCPMC9059946
OpenAlexW2910128713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.