Evidence map›Paper›PMID 35520307›Full record

ArticleRSC advances2020

Folic acid-conjugated magnetic mesoporous silica nanoparticles loaded with quercetin: a theranostic approach for cancer management.

Snehasis Mishra, Krishnendu Manna, Utpal Kayal, Moumita Saha, Sauvik Chatterjee, Debraj Chandra, Michikazu Hara, Sriparna Datta, Asim Bhaumik, Krishna Das Saha

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 68 citations in OpenAlex.

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  13. Berberine enhances the sensitivity of radiotherapy in ovarian cancer cell line (SKOV-3).Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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  18. A comparative assessment ofRSC advances · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Snehasis MishraCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullick Road Kolkata-700032 West Bengal India krishna@iicb.res.in +91 33 2473 5197 +91 33 2499 5810.
Krishnendu MannaCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullick Road Kolkata-700032 West Bengal India krishna@iicb.res.in +91 33 2473 5197 +91 33 2499 5810.
Utpal KayalSchool of Materials Sciences, Indian Association of Cultivation of Science 2A & B, Raja S. C. Mullick Road Kolkata-700032 West Bengal India msab@iacs.res.in +91-33-2473-2805 +91-33-2473-4971.
Moumita SahaCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullick Road Kolkata-700032 West Bengal India krishna@iicb.res.in +91 33 2473 5197 +91 33 2499 5810.
Sauvik ChatterjeeSchool of Materials Sciences, Indian Association of Cultivation of Science 2A & B, Raja S. C. Mullick Road Kolkata-700032 West Bengal India msab@iacs.res.in +91-33-2473-2805 +91-33-2473-4971.
Debraj ChandraWorld Research Hub Initiative (WRHI), Institute of Innovative Research, Tokyo Institute of Technology Nagatsuta-cho 4259, Midori-ku Yokohama 226-8503 Japan.ORCID https://orcid.org/0000-0002-5408-5092
Michikazu HaraLaboratory for Materials and Structures, Institute of Innovative Research, Tokyo Institute of Technology Nagatsuta-cho 4259, Midori-ku Yokohama 226-8503 Japan.ORCID https://orcid.org/0000-0003-3450-5704
Sriparna DattaDepartment of Chemical Technology, University of Calcutta Kolkata-700009 West Bengal India.
Asim BhaumikSchool of Materials Sciences, Indian Association of Cultivation of Science 2A & B, Raja S. C. Mullick Road Kolkata-700032 West Bengal India msab@iacs.res.in +91-33-2473-2805 +91-33-2473-4971.ORCID https://orcid.org/0000-0002-4907-7418
Krishna Das SahaCancer Biology and Inflammatory Disorder Division, CSIR-Indian Institute of Chemical Biology 4, Raja S. C. Mullick Road Kolkata-700032 West Bengal India krishna@iicb.res.in +91 33 2473 5197 +91 33 2499 5810.ORCID https://orcid.org/0000-0002-9286-4986
Indian Association for the Cultivation of Science · INIndian Institute of Chemical Biology · INTokyo Institute of Technology · JPUniversity of Calcutta · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of drug carriers based on nanomaterials that can selectively carry chemotherapeutic agents to cancer cells has become a major focus in biomedical research. A novel pH-sensitive multifunctional envelope-type mesoporous silica nanoparticle (SBA-15) was fabricated for targeted drug delivery to human colorectal carcinoma cells (HCT-116). SBA-15 was functionalized with folic acid (FA), and the material was loaded with the water-insoluble flavonoid, quercetin (QN). Additionally, acid-labile magnetite Fe

Identifiers

PMID35520307
PMCPMC9054720
OpenAlexW3036241338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.