ArticleClinical epidemiology2022
Identification of Childhood-Onset Inflammatory Bowel Disease in Swedish Healthcare Registers: A Validation Study.
Article in Clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Maternal autoimmune diseases during pregnancy and mortality up to young adulthood in offspring: a register-based cohort study.EClinicalMedicine · 2026Article
- Timing of complementary food introduction is not associated with inflammatory bowel disease risk: A prospective birth cohort study.Inflammatory bowel diseases · 2026Article
- Declining rates of surgery in pediatric-onset inflammatory bowel disease: a Swedish nationwide register-based cohort study 2002-2022.Journal of Crohn's & colitis · 2026Article
- Vedolizumab vs TNF Antagonists and Long-Term Outcomes in Ulcerative Colitis.JAMA network open · 2026Article
- Modifiable lifestyle factors in early life and inflammatory bowel disease risk in two birth cohorts.Journal of Crohn's & colitis · 2026Article
- Trends in Use of Prescribed Opioids in Incident and Prevalent Patients With Ulcerative Colitis: A Nationwide Study in Sweden.Inflammatory bowel diseases · 2026Article
- Corticosteroid Use in Childhood-Onset Inflammatory Bowel Disease: A Nationwide Cohort Study (2006-2022).United European gastroenterology journal · 2026Article
- Treatment-Free Outcomes Following Surgery for IBD: A Nationwide Cohort Study.Alimentary pharmacology & therapeutics · 2026Article
- Association of histologic and clinical activity with major adverse cardiovascular events in patients with inflammatory bowel disease: A cohort study.Journal of internal medicine · 2025Article
- Higher Prescribed Opioid Use Among Adults With Crohn's Disease Than General Population: A Nationwide Cohort Study in Sweden 2006-2021.Alimentary pharmacology & therapeutics · 2025Article
- Thiopurines and Intrahepatic Cholestasis of Pregnancy in Systemic Lupus Erythematosus and Inflammatory Bowel Disease Pregnancies.The American journal of gastroenterology · 2025Article
- Outcomes of inflammatory bowel disease in patients with obesity following bariatric surgery: propensity score-matched cohort study.BJS open · 2025Article
- Substantial Reduction of Systemic Corticosteroid Use After Primary Ileocaecal Resection in Swedish Patients With Crohn's Disease: A Population-Based Cohort Study.Alimentary pharmacology & therapeutics · 2025Article
- Diagnostic accuracy in the Swedish national patient register: a review including diagnoses in the outpatient register.European journal of epidemiology · 2025Review
- Childhood-onset inflammatory bowel disease and chronic non-bacterial osteomyelitis: a Swedish nationwide cohort study 2002-2022.Journal of Crohn's & colitis · 2025Article
- Bidirectional association between inflammatory bowel disease and type 1 diabetes: a nationwide matched cohort and case-control study.The Lancet regional health. Europe · 2024Article
- Childhood Socioeconomic Characteristics and Risk of Inflammatory Bowel Disease: A Scandinavian Birth Cohort Study.Inflammatory bowel diseases · 2024Article
- Early-Life Hygiene-Related Factors and Risk of Inflammatory Bowel Disease: A Scandinavian Birth Cohort Study.Inflammatory bowel diseases · 2024Article
- Spondyloarthritis in First-Degree Relatives and Spouses of Patients with Inflammatory Bowel Disease: A Nationwide Population-based Cohort Study from Sweden.Journal of Crohn's & colitis · 2024Article
- Risk of heart failure in inflammatory bowel disease: a Swedish population-based study.European heart journal · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The Swedish National Patient Register (NPR) is often used in observational studies of childhood-onset inflammatory bowel disease (IBD) (<18 years of age) and its subtypes, but the validity of previously used register-based algorithms for capturing childhood-onset IBD has never been examined. Methods: We identified a random sample of 233 individuals with at least two first ever diagnostic listings of IBD in the NPR between 2002 and 2014. We calculated the test characteristics for different register-based definitions of IBD and its subtypes using the Copenhagen criteria and the revised Porto criteria as gold standard, both based on medical chart review. We made assumptions of the occurrence of undiagnosed IBD in the general child population based on available literature. Results: Out of 233 individuals with at least two diagnostic listings of IBD, 216 had true IBD, resulting in a positive predictive value (PPV) = 93% (95% confidence interval (CI) 89-96), sensitivity = 88% (95% CI 83-92), specificity = 100% (95% CI 100-100), and negative predictive value (NPV) = 100% (95% CI 100-100). The PPV for the NPR-based definitions of IBD subtypes at time of first IBD diagnosis and at end of follow-up were 78% (95% CI 69-86) and 88% (95% CI 80-94), respectively, for Crohn's disease and 74% (95% CI 63-83) and 71% (95% CI 60-80), respectively, for ulcerative colitis. Conclusion: The validity of register-based definitions of childhood-onset IBD in the Swedish NPR is high and can be used to identify patients in observational research.
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