ArticleRSC advances2019
Different diameters of titanium dioxide nanotubes modulate Saos-2 osteoblast-like cell adhesion and osteogenic differentiation and nanomechanical properties of the surface.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications.Chemical record (New York, N.Y.) · 2026Review
- Nanotube Size Alters Corrosion Behavior, Mechanical Properties, and Biological Interactions of Anodized Ti6Al7Nb.ACS omega · 2026Article
- Article
- Graphene Oxide-Modified Titanium Dioxide Nanotubes Promote Schwann Cell Function and Neurotrophic Factor Expression.Journal of functional biomaterials · 2026Article
- Nanotopography-Mediated Mechanotransduction Enhances hBMSCs Adhesion on TiOJournal of functional biomaterials · 2026Article
- Nanotechnology for Biomedical Applications: Synthesis and Properties of Ti-Based Nanocomposites.Nanomaterials (Basel, Switzerland) · 2025Review
- The impact of anodization modification on titanium interaction with human osteoblasts and fibroblasts (in vitro study).PloS one · 2025Article
- Creating an extracellular matrix-like three-dimension structure to enhance the corrosion resistance and biological responses of titanium implants.Journal of dental sciences · 2024Article
- Insight into antibacterial effect of titanium nanotubular surfaces with focus on Staphylococcus aureus and Pseudomonas aeruginosa.Scientific reports · 2024Article
- Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation.Bioactive materials · 2023Review
- Effect of Silicon Carbide Coating on Osteoblast Mineralization of Anodized Titanium Surfaces.Journal of functional biomaterials · 2022Article
- Recovering Osteoblast Functionality on TiOInternational journal of nanomedicine · 2022Article
- The Deposition of a Lectin fromBiomolecules · 2021Article
- Deciphering controversial results of cell proliferation on TiORegenerative biomaterials · 2021Article
- RhBMP-2-Loaded PLGA/Titanium Nanotube Delivery System Synergistically Enhances Osseointegration.ACS omega · 2021Article
- Mesenchymal stem cell interaction with TiRSC advances · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The formation of nanostructures on titanium implant surfaces is a promising strategy to modulate cell adhesion and differentiation, which are crucial for future application in bone regeneration. The aim of this study was to investigate how the nanotube diameter and/or nanomechanical properties alter human osteoblast like cell (Saos-2) adhesion, growth and osteogenic differentiation
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.