Evidence map›Paper›PMID 35520156›Full record

ArticleRSC advances2019

Enhancement of protein stability by an additional disulfide bond designed in human neuroglobin.

Hai-Xiao Liu, Lianzhi Li, Xin-Zhi Yang, Chuan-Wan Wei, Hui-Min Cheng, Shu-Qin Gao, Ge-Bo Wen, Ying-Wu Lin

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Site-specific incorporation ofCommunications biology · 2024
    Article
  3. Stabilization ofMembranes · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hai-Xiao LiuSchool of Chemistry and Chemical Engineering, University of South China Hengyang 421001 China linlinying@hotmail.com ywlin@usc.edu.cn.ORCID https://orcid.org/0000-0003-4432-5010
Lianzhi LiSchool of Chemistry and Chemical Engineering, Liaocheng University Liaocheng 252059 China.ORCID https://orcid.org/0000-0002-8447-3803
Xin-Zhi YangLaboratory of Protein Structure and Function, University of South China Hengyang 421001 China.
Chuan-Wan WeiSchool of Chemistry and Chemical Engineering, University of South China Hengyang 421001 China linlinying@hotmail.com ywlin@usc.edu.cn.
Hui-Min ChengSchool of Chemistry and Chemical Engineering, University of South China Hengyang 421001 China linlinying@hotmail.com ywlin@usc.edu.cn.
Shu-Qin GaoLaboratory of Protein Structure and Function, University of South China Hengyang 421001 China.
Ge-Bo WenLaboratory of Protein Structure and Function, University of South China Hengyang 421001 China.
Ying-Wu LinSchool of Chemistry and Chemical Engineering, University of South China Hengyang 421001 China linlinying@hotmail.com ywlin@usc.edu.cn.ORCID https://orcid.org/0000-0002-2457-0871
Hengyang Academy of Agricultural Sciences · CNLiaocheng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human neuroglobin (Ngb) forms an intramolecular disulfide bond between Cys46 and Cys55, with a third Cys120 near the protein surface, which is a promising protein model for heme protein design. In order to protect the free Cys120 and to enhance the protein stability, we herein developed a strategy by designing an additional disulfide bond between Cys120 and Cys15

Identifiers

PMID35520156
PMCPMC9062612
OpenAlexW2914668536

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.