Evidence map›Paper›PMID 35520091›Full record

ArticleRSC advances2020

Aryldiazoquinoline based multifunctional small molecules for modulating Aβ

Monika Rana, Abhishek Pareek, Shivani Bhardwaj, Geeta Arya, Surendra Nimesh, Hemant Arya, Tarun K Bhatt, Srinivasarao Yaragorla, Anuj K Sharma

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monika RanaDepartment of Chemistry, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India anuj.sharma@curaj.ac.in aks.iitk@gmail.com.
Abhishek PareekSchool of Chemistry, University of Hyderabad, P.O. Central University Hyderabad 5000046 Telangana State India Srinivas.yaragorla@uohyd.ac.in.
Shivani BhardwajDepartment of Chemistry, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India anuj.sharma@curaj.ac.in aks.iitk@gmail.com.
Geeta AryaDepartment of Biotechnology, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India.
Surendra NimeshDepartment of Biotechnology, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India.ORCID https://orcid.org/0000-0003-3222-1097
Hemant AryaDepartment of Biotechnology, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India.
Tarun K BhattDepartment of Biotechnology, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India.
Srinivasarao YaragorlaSchool of Chemistry, University of Hyderabad, P.O. Central University Hyderabad 5000046 Telangana State India Srinivas.yaragorla@uohyd.ac.in.ORCID https://orcid.org/0000-0001-6152-5861
Anuj K SharmaDepartment of Chemistry, Central University of Rajasthan NH-8, Bandarsindri Ajmer Rajasthan 305817 India anuj.sharma@curaj.ac.in aks.iitk@gmail.com.ORCID https://orcid.org/0000-0002-5090-3713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research continues to find a breakthrough for the treatment of Alzheimer's Disease (AD) due to its complicated pathology. Presented herein is a novel series of arydiazoquinoline molecules investigated for their multifunctional properties against the factors contributing to Alzheimer's disease (AD). The inhibitory properties of fourteen closely related aryldiazoquinoline derivatives have been evaluated for their inhibitory effect on Aβ

Identifiers

PMID35520091
PMCPMC9055851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.