ArticleRSC advances2019
Mesoporous semiconductors combined with up-conversion nanoparticles for enhanced photodynamic therapy under near infrared light.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Recent advances of lanthanide nanomaterials in Tumor NIR fluorescence detection and treatment.Materials today. Bio · 2023Review
- Reactive Oxygen Species-Regulating Strategies Based on Nanomaterials for Disease Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Novel one pot synthesis and spectroscopic characterization of a folate-MnRSC advances · 2019Article
- Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photodynamic therapy (PDT) is a promising and effective method for tumor therapy that relies on the reactive oxygen species (ROS) produced by photosensitizers at specific wavelengths to inhibit tumor cells. Inorganic semiconductive materials are potential photosensitizers that can excellently absorb ultraviolet light to produce ROS to kill cancer cells. However, this strategy is still limited in terms of practical applications due to the weak penetration of ultraviolet light through biological tissue, as well as the hypoxic tumor microenvironment, largely decreasing ROS generation. In this research, novel PDT agents made with mesoporous lanthanide-semiconductor composites are developed to obtain a remarkable amount of generated ROS under near-infrared (NIR) laser irradiation. Due to the larger size (about 120 nm) of the up-conversion material (UCM) used as the substrate, coated with different amounts of semiconductors with mesoporous morphologies, this platform could emit higher blue emission under a 980 nm laser. Meanwhile, both of the semiconductors (SnO
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Registered trials
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