Evidence map›Paper›PMID 35519840›Full record

ArticleRSC advances2019

Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(ii) polypyridyl complex.

Stephanie Mehanna, Najwa Mansour, Hassib Audi, Kikki Bodman-Smith, Mohamad A Mroueh, Robin I Taleb, Costantine F Daher, Rony S Khnayzer

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie MehannaDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.
Najwa MansourDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.
Hassib AudiDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.
Kikki Bodman-SmithFaculty of Health and Medical Sciences, Department of Microbial and Cellular Sciences, University of Surrey UK.
Mohamad A MrouehSchool of Pharmacy, Department of Pharmaceutical Sciences, Lebanese American University Lebanon.
Robin I TalebDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.ORCID https://orcid.org/0000-0001-8033-6951
Costantine F DaherDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.ORCID https://orcid.org/0000-0002-8275-7263
Rony S KhnayzerDepartment of Natural Sciences, Lebanese American University Chouran Beirut 1102-2801 Lebanon rony.khnayzer@lau.edu.lb.ORCID https://orcid.org/0000-0001-7775-0027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of ruthenium complexes as chemotherapeutic agents has been recently explored as one of the alternatives to conventional treatments. In the present study, two Ru(ii) polypyridyl complexes were synthesized and characterized: a strained [Ru(bipy)

Identifiers

PMID35519840
PMCPMC9064604

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.