Evidence map›Paper›PMID 35519406›Full record

ArticleRSC advances2019

Micronutrients encapsulation in enhanced nanoliposomal carriers by a novel preparative technology.

Annalisa Dalmoro, Sabrina Bochicchio, Gaetano Lamberti, Paolo Bertoncin, Barbara Janssens, Anna Angela Barba

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  12. Potential of Nanonutraceuticals in Increasing Immunity.Nanomaterials (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annalisa DalmoroEng4Life Srl, Spin-off Accademico Via Fiorentino, 32 83100 Avellino Italy.
Sabrina BochicchioEng4Life Srl, Spin-off Accademico Via Fiorentino, 32 83100 Avellino Italy.
Gaetano LambertiEng4Life Srl, Spin-off Accademico Via Fiorentino, 32 83100 Avellino Italy.ORCID https://orcid.org/0000-0003-1689-6887
Paolo BertoncinDipartimento di Scienze della Vita - Centro Microscopia Elettronica, Università degli Studi di Trieste Via Fleming 31, A/B 34127 Trieste Italy.
Barbara JanssensDepartment of Pharmaceutics, University of Gent Sint-Pietersnieuwstraat 25 9000 Belgium.
Anna Angela BarbaEng4Life Srl, Spin-off Accademico Via Fiorentino, 32 83100 Avellino Italy.ORCID https://orcid.org/0000-0003-3144-4598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micronutrients administration by fortification of staple and complementary foods is a followed strategy to fight malnutrition and micronutrient deficiencies and related pathologies. There is a great industrial interest in preparation of formulations for joint administration of vitamin D3 and vitamin K2 for providing bone support, promoting heart health and helping boost immunity. To respond to this topic, in this work, uncoated nanoliposomes loaded with vitamin D3 and K2 were successfully prepared, by using a novel, high-yield and semi continuous technique based on simil-microfluidic principles. By the same technique, to promote and to enhance mucoadhesiveness and stability of the produced liposomal structures, chitosan was tested as covering material. By this way polymer-lipid hybrid nanoparticles, encapsulating vitamin D3 and vitamin K2, with improved features in terms of stability, loading and mucoadhesiveness were produced for potential nutraceutical and pharmaceutical applications.

Identifiers

PMID35519406
PMCPMC9065329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.