Evidence map›Paper›PMID 35519277›Full record

ArticleBiomedical optics express2022

Surgical scene generation and adversarial networks for physics-based iOCT synthesis.

Michael Sommersperger, Alejandro Martin-Gomez, Kristina Mach, Peter Louis Gehlbach, M Ali Nasseri, Iulian Iordachita, Nassir Navab

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Robotic Navigation Autonomy for Subretinal Injection via Intelligent Real-Time Virtual iOCT Volume Slicing.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael SommerspergerChair for Computer Aided Medical Procedures and Augmented Reality, Informatics Department, Technical University of Munich, Munich, Bayern, Germany.
Alejandro Martin-GomezChair for Computer Aided Medical Procedures and Augmented Reality, Informatics Department, Technical University of Munich, Munich, Bayern, Germany.ORCID https://orcid.org/0000-0001-9341-3477
Kristina MachChair for Computer Aided Medical Procedures and Augmented Reality, Informatics Department, Technical University of Munich, Munich, Bayern, Germany.
Peter Louis GehlbachWilmer Eye Institute Research, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
M Ali NasseriKlinikum Rechts der Isar, Augenklinik, Munich, Bayern, Germany.
Iulian IordachitaLaboratory for Computational Sensing and Robotics, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Nassir NavabChair for Computer Aided Medical Procedures and Augmented Reality, Informatics Department, Technical University of Munich, Munich, Bayern, Germany.

Funding

Enabling technology for image-guided robot-assisted sub-retinal injectionsR01EB025883 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI IORDACHITA, IULIAN IOAN · 2019 to 2021
$1.5M
NIBIB NIH HHS R01 EB025883
6 · The paper itself

Abstract

The development and integration of intraoperative optical coherence tomography (iOCT) into modern operating rooms has motivated novel procedures directed at improving the outcome of ophthalmic surgeries. Although computer-assisted algorithms could further advance such interventions, the limited availability and accessibility of iOCT systems constrains the generation of dedicated data sets. This paper introduces a novel framework combining a virtual setup and deep learning algorithms to generate synthetic iOCT data in a simulated environment. The virtual setup reproduces the geometry of retinal layers extracted from real data and allows the integration of virtual microsurgical instrument models. Our scene rendering approach extracts information from the environment and considers iOCT typical imaging artifacts to generate cross-sectional label maps, which in turn are used to synthesize iOCT B-scans via a generative adversarial network. In our experiments we investigate the similarity between real and synthetic images, show the relevance of using the generated data for image-guided interventions and demonstrate the potential of 3D iOCT data synthesis.

Identifiers

PMID35519277
PMCPMC9045909

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.