Evidence map›Paper›PMID 35519269›Full record

ArticleBiomedical optics express2022

Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging.

Omar B Osman, Zachery B Harris, Mahmoud E Khani, Juin W Zhou, Andrew Chen, Adam J Singer, M Hassan Arbab

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Review
  6. Triage ofBiomedical optics express · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omar B OsmanState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.ORCID https://orcid.org/0000-0002-0943-6703
Zachery B HarrisState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.ORCID https://orcid.org/0000-0002-6557-6225
Mahmoud E KhaniState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.ORCID https://orcid.org/0000-0002-3058-6247
Juin W ZhouState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.
Andrew ChenState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.
Adam J SingerRenaissance School of Medicine at Stony Brook University, Department of Emergency Medicine, 101 Nicolls Rd., Stony Brook, NY 11794, USA.
M Hassan ArbabState University of New York at Stony Brook, THz Biophotonics Laboratory, Department of Biomedical Engineering, 101 Nicolls Rd., Stony Brook, NY 11794, USA.ORCID https://orcid.org/0000-0002-6565-3358

Funding

Noninvasive Broadband Terahertz Assessment of Burn SeverityR01GM112693 · NIGMS · UNIVERSITY OF WASHINGTON · PI ARBAB, M. HASSAN · 2015 to 2019
$2.6M
NIGMS NIH HHS R01 GM112693
6 · The paper itself

Abstract

Thermal injuries can occur due to direct exposure to hot objects or liquids, flames, electricity, solar energy and several other sources. If the resulting injury is a deep partial thickness burn, the accuracy of a physician's clinical assessment is as low as 50-76% in determining the healing outcome. In this study, we show that the Terahertz Portable Handheld Spectral Reflection (THz-PHASR) Scanner combined with a deep neural network classification algorithm can accurately differentiate between partial-, deep partial-, and full-thickness burns 1-hour post injury, regardless of the etiology, scanner geometry, or THz spectroscopy sampling method (ROC-AUC = 91%, 88%, and 86%, respectively). The neural network diagnostic method simplifies the classification process by directly using the pre-processed THz spectra and removing the need for any hyperspectral feature extraction. Our results show that deep learning methods based on THz time-domain spectroscopy (THz-TDS) measurements can be used to guide clinical treatment plans based on objective and accurate classification of burn injuries.

Identifiers

PMID35519269
PMCPMC9045889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.