Evidence map›Paper›PMID 35519268›Full record

ArticleBiomedical optics express2022

Diamond Raman laser and Yb fiber amplifier for

Shaun A Engelmann, Annie Zhou, Ahmed M Hassan, Michael R Williamson, Jeremy W Jarrett, Evan P Perillo, Alankrit Tomar, David J Spence, Theresa A Jones, Andrew K Dunn

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Improving vascular retention of indocyanine green forJournal of biomedical optics · 2025
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  7. Pulse train gating to improve signal generation forbioRxiv : the preprint server for biology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Shaun A EngelmannDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.ORCID https://orcid.org/0000-0002-2410-896X
Annie ZhouDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.ORCID https://orcid.org/0000-0003-0479-2941
Ahmed M HassanDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.
Michael R WilliamsonInstitute for Neuroscience, The University of Texas at Austin, 2415 Speedway, Austin, TX 78712, USA.ORCID https://orcid.org/0000-0002-8049-4463
Jeremy W JarrettDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.ORCID https://orcid.org/0000-0003-1308-1519
Evan P PerilloDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.
Alankrit TomarDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.
David J SpenceMQ Photonics, Department of Physics and Astronomy, Macquarie University, NSW 2109, Australia.ORCID https://orcid.org/0000-0001-5974-853X
Theresa A JonesInstitute for Neuroscience, The University of Texas at Austin, 2415 Speedway, Austin, TX 78712, USA.
Andrew K DunnDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton, Austin, TX 78712, USA.
The University of Texas at Austin · USMacquarie University · AU

Funding

Optical Imaging of Baseline Blood Flow and Oxygenation During StrokeR01EB011556 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K · 2010 to 2018
$3.1M
Longitudinal Imaging of Cortical Small Vessel Network Structure with Two-Color Multiphoton Fluorescence MicroscopyR01NS108484 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K · 2018 to 2022
$2.8M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
PREDOCTORAL TRAINING IN BIOMEDICAL BIG DATA SCIENCET32LM012414 · NLM · UNIVERSITY OF TEXAS AT AUSTIN · PI DHILLON, INDERJIT, MEYERS, LAUREN ANCEL · 2016 to 2020
$974k
NIBIB NIH HHS R01 EB011556NIBIB NIH HHS T32 EB007507NINDS NIH HHS R01 NS108484NLM NIH HHS T32 LM012414
6 · The paper itself

Abstract

Here we introduce a fiber amplifier and a diamond Raman laser that output high powers (6.5 W, 1.3 W) at valuable wavelengths (1060 nm, 1250 nm) for two-photon excitation of red-shifted fluorophores. These custom excitation sources are both simple to construct and cost-efficient in comparison to similar custom and commercial alternatives. Furthermore, they operate at a repetition rate (80 MHz) that allows fast image acquisition using resonant scanners. With our system we demonstrate compatibility with fast resonant scanning, the ability to acquire neuronal images, and the capability to image vasculature at deep locations (>1 mm) within the mouse cerebral cortex.

Identifiers

PMID35519268
PMCPMC9045921
OpenAlexW4220726767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.