Evidence map›Paper›PMID 35519266›Full record

ArticleBiomedical optics express2022

Brain white matter morphological structure correlation with its optical properties estimated from optical coherence tomography (OCT) data.

Alexander A Moiseev, Ksenia A Achkasova, Elena B Kiseleva, Konstantin S Yashin, Arseniy L Potapov, Evgenia L Bederina, Sergey S Kuznetsov, Evgeny P Sherstnev, Dmitry V Shabanov, Grigory V Gelikonov and 2 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Sex as a Determinant of Age-Related Changes in the Brain.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander A MoiseevInstitute of Applied Physics Russian Academy of Sciences, 603155, 46, Ulyanova str., Nizhny Novgorod, Russia.
Ksenia A AchkasovaPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.ORCID https://orcid.org/0000-0001-8768-000X
Elena B KiselevaPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.ORCID https://orcid.org/0000-0003-4769-417X
Konstantin S YashinPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.
Arseniy L PotapovPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.ORCID https://orcid.org/0000-0003-4343-2500
Evgenia L BederinaPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.
Sergey S KuznetsovN.A. Semashko Nizhny Novgorod Regional Clinical Hospital, 603093, 190, Rodionova str., Nizhny Novgorod, Russia.
Evgeny P SherstnevInstitute of Applied Physics Russian Academy of Sciences, 603155, 46, Ulyanova str., Nizhny Novgorod, Russia.
Dmitry V ShabanovInstitute of Applied Physics Russian Academy of Sciences, 603155, 46, Ulyanova str., Nizhny Novgorod, Russia.
Grigory V GelikonovInstitute of Applied Physics Russian Academy of Sciences, 603155, 46, Ulyanova str., Nizhny Novgorod, Russia.ORCID https://orcid.org/0000-0002-0798-4570
Yuliya V OstrovskayaDentistry clinic "IQDent", 105120, 10, 2nd Syromyatnichesky Lane, Moscow, Russia.
Natalia D GladkovaPrivolzhsky Research Medical University, 603950, 10/1, Minin and Pozharsky sq., Nizhny Novgorod, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A pilot post-mortem study identifies a strong correlation between the attenuation coefficient estimated from the OCT data and some morphological features of the sample, namely the number of nuclei in the field of view of the histological image and the fiber structural parameter introduced in the study to quantify the difference in the myelinated fibers arrangements. The morphological features were identified from the histopathological images of the sample taken from the same locations as the OCT images and stained with the immunohistochemical (IHC) staining specific to the myelin. It was shown that the linear regression of the IHC quantitative characteristics allows adequate prediction of the attenuation coefficient of the sample. This discovery opens the opportunity for the usage of the OCT as a neuronavigation tool.

Identifiers

PMID35519266
PMCPMC9045907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.