ArticleBiomedical optics express2022
Cherenkov light emission in molecular radiation therapy of the thyroid and its application to dosimetry.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- In-silico investigation into optimal photoacoustic probe design using a digital thyroid phantom.Journal of biomedical optics · 2027Article
- Optical (Cherenkov) dosimetry to unravel the radiobiological effects of radioisotope based therapy.European journal of nuclear medicine and molecular imaging · 2025Article
- Cherenkov light emission in external beam radiation therapy of the larynx.Journal of biomedical optics · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Numerical experiments based on Monte Carlo simulations and clinical CT data are performed to investigate the spatial and spectral characteristics of Cherenkov light emission and the relationship between Cherenkov light intensity and deposited dose in molecular radiotherapy of hyperthyroidism and papillary thyroid carcinoma. It is found that Cherenkov light is emitted mostly in the treatment volume, the spatial distribution of Cherenkov light at the surface of the patient presents high-value regions at locations that depend on the symmetry and location of the treatment volume, and the surface light in the near-infrared spectral region originates from the treatment site. The effect of inter-patient variability in the tissue optical parameters and radioisotope uptake on the linear relationship between the dose absorbed by the treatment volume and Cherenkov light intensity at the surface of the patient is investigated, and measurements of surface light intensity for which this effect is minimal are identified. The use of Cherenkov light measurements at the patient surface for molecular radiation therapy dosimetry is also addressed.
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Registered trials
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