ArticleThe Pan African medical journal2022
Prevalence and predictors of renal dysfunction among people living with HIV on antiretroviral therapy in the Southern Highland of Tanzania: a hospital-based cross-sectional study.
Article in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Prevalence of chronic kidney diseases among people living with HIV in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Kidney dysfunction and associated factors among adults living with human immuno-deficiency virus in Africa: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Acute kidney injury and its predictors among HIV-positive patients in Africa: Systematic review and meta-analysis.PloS one · 2024Pooled it
- Age-dependent mitochondrial toxicity in renal stem cells: A precise 3D silk matrix model.Genes & diseases · 2026Article
- Kidney dysfunction and its associated factors among people living with HIV on antiretroviral therapy in rural Rwanda: a cross-sectional study.BMC infectious diseases · 2026Article
- Article
- Modeling the impact of antiretroviral therapy on HIV and related kidney diseases in Tanzania.Scientific reports · 2025Article
- Prevalence and predictors of kidney dysfunction among people living with HIV in Tanzania.PLOS global public health · 2025Article
- Point of care creatinine testing for early detection of renal dysfunction in Tanzanian HIV patients: a study protocol.BMC nephrology · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
Introduction: infection with Human Immunodeficiency Virus (HIV) and use of antiretroviral therapy (ART) poses a significant risk of developing renal dysfunction in people living with HIV (PLHIV). Renal dysfunction contributes to the morbidity and mortality of PLHIV. There is limited information on renal dysfunction among PLHIV in the Southern Highland, the highest HIV prevalent area in Tanzania. We conducted a study to estimate the magnitude and predictors of renal dysfunction among PLHIV on ART. Methods: a cross-sectional study was conducted at Njombe Town Council Hospital from December 2019 to April 2020, recruiting 396 participants. Serum was obtained to measure creatinine level then calculated glomerular filtration rate (GFR) using CKD-EPI and the Bedside Schwartz equations. The participants' informations were collected using a structured questionnaire. Data analysis was performed using STATA version 15; a modified Poisson regression model was used to estimate prevalence ratios (PR). The level of significance was specified at 0.05. Results: the overall prevalence of renal dysfunction defined as GFR less than 90 mL/min/1.73 m Conclusion: there is a relatively high prevalence of renal dysfunction among PLHIV on ART, predicted by age, duration on ART, and nutrition status.
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