Evidence map›Paper›PMID 35519040›Full record

ArticleRSC advances2020

Microencapsulated UV filter@ZIF-8 based sunscreens for broad spectrum UV protection.

Anu Sharma, Abhishek Kumar, Changning Li, Rakesh Kumar Sharma, Mark T Swihart

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anu SharmaDepartment of Chemistry, University of Delhi India sharmark101@yahoo.com.ORCID https://orcid.org/0000-0002-8661-1165
Abhishek KumarDepartment of Chemical and Biological Engineering, University at Buffalo (SUNY) USA swihart@buffalo.edu.ORCID https://orcid.org/0000-0003-3989-7815
Changning LiDepartment of Chemical and Biological Engineering, University at Buffalo (SUNY) USA swihart@buffalo.edu.ORCID https://orcid.org/0000-0002-2216-3594
Rakesh Kumar SharmaDepartment of Chemistry, University of Delhi India sharmark101@yahoo.com.
Mark T SwihartDepartment of Chemical and Biological Engineering, University at Buffalo (SUNY) USA swihart@buffalo.edu.ORCID https://orcid.org/0000-0002-9652-687X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sunscreens play a vital role in protecting human skin from photodamage upon UV exposure, but their effectiveness is limited by degradation and phototoxicity. Photoactivation of UV filters in sunscreen can generate reactive oxygen species, with accompanying cytotoxicity. Herein, we report stable, safe, fluorescent, and long-lasting sunscreens produced by microencapsulation of organic UV filters octylmethoxycinnamate (OMC) and butyl-methoxydibenzoylmethane (BMDM), alone and together, into a microporous zeolitic imidazole framework (ZIF-8). The visibly transparent OMC + BMDM@ZIF-8 sunscreens displayed complete broad-spectrum photoprotection against UV light even after 24 hours. Photostability testing of the sunscreens demonstrated the photo-protective nature of microporous ZIF-8 for stabilizing these UV filters. The sun protection factor (SPF) values for lotions containing 10% (w/w) OMC@ZIF-8, BMDM@ZIF-8 and OMC + BMDM@ZIF-8 sunscreens decreased from 29.8 to 26.0, 32.5 to 26.4, and 62.1 to 53.0, respectively, upon 24 hours of intense UV exposure. No release of the UV filters from the encapsulated formulations was observed. The ZIF-8 particles are too large to be transported across the stratum corneum. Thus, our findings suggest that zeolitic framework-encapsulated sunscreens could provide prolonged UV-protection efficacy and ultra-high SPF with reduced potential for degradation, phototoxicity, and transport across the skin.

Identifiers

PMID35519040
PMCPMC9056713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.