Evidence map›Paper›PMID 35518939›Full record

ArticleFrontiers in endocrinology2022

Genetic Etiology of Neonatal Diabetes Mellitus in Vietnamese Infants and Characteristics of Those With

Can Thi Bich Ngoc, Vu Chi Dung, Elisa De Franco, Nguyen Ngoc Lan, Bui Phuong Thao, Nguyen Ngoc Khanh, Sarah E Flanagan, Maria E Craig, Nguyen Huy Hoang, Tran Minh Dien

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Permanent Neonatal Diabetes with High Insulin Requirements due to a New Variant in theJournal of clinical research in pediatric endocrinology · 2026
    Article
  2. Neonatal and Syndromic Forms of Diabetes.Current diabetes reports · 2025
    Review
  3. Neonatal diabetes mellitus around the world: Update 2024.Journal of diabetes investigation · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Can Thi Bich NgocThe Center of Endocrinology, Metabolism, Genetics, and Molecular Therapy, Vietnam National Children's Hospital, Hanoi, Vietnam.
Vu Chi DungThe Center of Endocrinology, Metabolism, Genetics, and Molecular Therapy, Vietnam National Children's Hospital, Hanoi, Vietnam.
Elisa De FrancoInstitute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
Nguyen Ngoc LanInstitute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Bui Phuong ThaoThe Center of Endocrinology, Metabolism, Genetics, and Molecular Therapy, Vietnam National Children's Hospital, Hanoi, Vietnam.
Nguyen Ngoc KhanhThe Center of Endocrinology, Metabolism, Genetics, and Molecular Therapy, Vietnam National Children's Hospital, Hanoi, Vietnam.
Sarah E FlanaganInstitute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
Maria E CraigInstitute of Endocrinology and Diabetes, The Children's Hospital at Westmead/Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia.
Nguyen Huy HoangInstitute of Genome Research, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Tran Minh DienThe Center of Endocrinology, Metabolism, Genetics, and Molecular Therapy, Vietnam National Children's Hospital, Hanoi, Vietnam.
National Hospital of Pediatrics · VNUniversity of Exeter · GBVietnam Academy of Science and Technology · VNUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neonatal diabetes mellitus (NDM) is a rare (1:90,000 newborns) but potentially devastating metabolic disorder characterized by hyperglycemia combined with low levels of insulin. Dominantly-acting insulin ( Patients and Methods: The study included 70 infants diagnosed with NDM in the first year of life between May 2008 and May 2021 at the Vietnam National Children's Hospital. Sequencing analysis of all the genes known to cause NDM was performed at the Exeter Genomic Laboratory, UK. Clinical characteristics, molecular genetics, and annual data relating to glycemic control (HbA1c) and severe hypoglycemia of those with Results: Fifty-five of 70 infants (78.5%) with NDM harbored a mutation in a known disease-causing gene and of these, 10 had six different Conclusions: We report a series of Vietnamese NDM cases with dominant

Indexed as

Diabetes MellitusDiabetic KetoacidosisInfant, Newborn, DiseasesAsian PeopleChildGlycated HemoglobinHumansInfantInfant, NewbornInsulinMutationVietnamGlycated HemoglobinInsulindiabetes mellitus in infantsINS mutationsneonatal diabetes mellitusneonatal diabetes mellitus in Vietnamese infantsoutcomes in infants with INS gene mutations

Identifiers

PMID35518939
PMCPMC9063464
OpenAlexW4224219966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.