ArticleFrontiers in endocrinology2022
The Association of Serum Total Bile Acids With Bone Mineral Density in Chinese Adults Aged 20-59: A Retrospective Cross-Sectional Study.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- The gut-bone axis: microbial metabolism and nutritional interventions for bone health.Gut microbes · 2026Review
- Roseburia intestinalis-derived extracellular vesicles alleviate osteoporosis through gut microbiota-regulated histidylleucine via Akt/FOXO1 signaling.Communications biology · 2026Article
- Gut Microbiota and SCFA Changes After Alendronate-Calcitriol Therapy in Postmenopausal Osteoporosis.International journal of women's health · 2026Article
- An explainable machine learning model for predicting osteoporotic fragility fractures: a retrospective study in South China.Frontiers in medicine · 2026Article
- Gut microbiota and microbial metabolites for osteoporosis.Gut microbes · 2025Review
- Gut-X Axis and Its Role in Poultry Bone Health: A Review.Microorganisms · 2025Review
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- The association between total bile acid and bone mineral density among patients with type 2 diabetes.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: According to a recent study, serum total bile acids (TBA) may preserve lumbar bone mineral density (BMD) in Cushing syndrome patients, and BMD is directly linked to bone health. We were interested in examining the association between TBA and in Chinese adults aged 20-59 years. Methods: We retrospectively analyzed the physical examination results of 2,490 general healthy subjects in Hainan West Central Hospital. Femoral neck BMD and TBA were measured, and the relationship between TBA and femoral neck BMD was evaluated by curve fitting, a generalized additive model, and multiple linear regression analysis. Results: The fitted smooth curve and generalized additive model showed a nonlinear relationship between TBA and femoral neck BMD, and a positive correlation between TBA and femoral neck BMD was found after we made adjustments for the potential confounders. Conclusion: TBA is positively associated with femoral neck BMD in Chinese adults aged 20-59 years.
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