Evidence map›Paper›PMID 35518684›Full record

ArticleRSC advances2019

Synthesis and characterisation of α-carboxynitrobenzyl photocaged l-aspartates for applications in time-resolved structural biology.

John J Zaitsev-Doyle, Anke Puchert, Yannik Pfeifer, Hao Yan, Briony A Yorke, Henrike M Müller-Werkmeister, Charlotte Uetrecht, Julia Rehbein, Nils Huse, Arwen R Pearson and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Using photocaging for fast time-resolved structural biology studies.Acta crystallographica. Section D, Structural biology · 2021
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John J Zaitsev-DoyleThe Hamburg Center for Ultrafast Imaging & Institute for Nanostructure and Solid State Physics Luruper Chaussee 149 22761 Hamburg Germany arwen.pearson@cfel.de marta.sans.valls@cfel.de.ORCID https://orcid.org/0000-0003-3874-1712
Anke PuchertDepartment of Physics and Centre for Hybrid Nanostructures, University of Hamburg Luruper Chaussee 149 22761 Hamburg Germany.ORCID https://orcid.org/0000-0002-5736-6922
Yannik PfeiferUniversity of Potsdam, Institute of Chemistry, Physical Chemistry Karl-Liebknecht-Str. 24-25, Golm 14476 Potsdam Germany.ORCID https://orcid.org/0000-0002-6574-2203
Hao YanHeinrich Pette Institute, Leibniz Institute for Experimental Virology Martinistrasse 52 20251 Hamburg Germany.ORCID https://orcid.org/0000-0002-3139-4597
Briony A YorkeSchool of Chemistry, University of Leeds Leeds LS2 9JT UK.ORCID https://orcid.org/0000-0002-1868-8435
Henrike M Müller-WerkmeisterUniversity of Potsdam, Institute of Chemistry, Physical Chemistry Karl-Liebknecht-Str. 24-25, Golm 14476 Potsdam Germany.ORCID https://orcid.org/0000-0001-9471-882X
Charlotte UetrechtHeinrich Pette Institute, Leibniz Institute for Experimental Virology Martinistrasse 52 20251 Hamburg Germany.ORCID https://orcid.org/0000-0002-1991-7922
Julia RehbeinFachbereich für Chemie und Pharmazie, Universität Regensburg Universitätsstrasse 31 93053 Regensburg Germany.ORCID https://orcid.org/0000-0001-9241-0637
Nils HuseThe Hamburg Center for Ultrafast Imaging & Institute for Nanostructure and Solid State Physics Luruper Chaussee 149 22761 Hamburg Germany arwen.pearson@cfel.de marta.sans.valls@cfel.de.ORCID https://orcid.org/0000-0002-3281-7600
Arwen R PearsonThe Hamburg Center for Ultrafast Imaging & Institute for Nanostructure and Solid State Physics Luruper Chaussee 149 22761 Hamburg Germany arwen.pearson@cfel.de marta.sans.valls@cfel.de.ORCID https://orcid.org/0000-0001-8499-7490
Marta SansThe Hamburg Center for Ultrafast Imaging & Institute for Nanostructure and Solid State Physics Luruper Chaussee 149 22761 Hamburg Germany arwen.pearson@cfel.de marta.sans.valls@cfel.de.ORCID https://orcid.org/0000-0002-0102-8190

Funding

Wellcome Trust
6 · The paper itself

Abstract

We report a new synthetic route to a series of α-carboxynitrobenzyl photocaged l-aspartates for application in time-resolved structural biology. The resulting compounds were characterised in terms of UV/Vis absorption properties, aqueous solubility and stability, and photocleavage rates (

Identifiers

PMID35518684
PMCPMC9061760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.