Evidence map›Paper›PMID 35518668›Full record

ArticleRSC advances2019

Enhancement of neural stem cell survival, proliferation and differentiation by IGF-1 delivery in graphene oxide-incorporated PLGA electrospun nanofibrous mats.

Zhiping Qi, Wenlai Guo, Shuang Zheng, Chuan Fu, Yue Ma, Su Pan, Qinyi Liu, Xiaoyu Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhiping QiDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Wenlai GuoDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Shuang ZhengDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Chuan FuDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Yue MaDepartment of Gynecological Oncology, The First Hospital of Jilin University Xinmin Street No. 71 Changchun TX 130000 PR China.
Su PanDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Qinyi LiuDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Xiaoyu YangDepartment of Orthopedic Surgery, The Second Hospital of Jilin University Ziqiang Street No. 218 Changchun TX 130041 Jilin PR China qinyi@jlu.edu.cn yangxiaoy@jlu.edu.cn.
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian central nervous system has a limited ability for self-repair under injury conditions. The treatment of nerve injuries has been revolutionised with the development of tissue engineering techniques. However, the lack of bioactivity has severely restricted the application of biodegradable implants for neurogenesis. Therefore, surface modification of biomaterials is crucial to improve their bioactivity and promote endogenous repair mechanisms for nerve regeneration. Insulin-like growth factor 1 (IGF-1) is a growth factor for neuroprotection and neurogenesis. In this study, IGF-1 was successfully immobilised on graphene oxide (GO)-incorporated poly(lactic-

Identifiers

PMID35518668
PMCPMC9061867
OpenAlexW2920997507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.