Evidence map›Paper›PMID 35518661›Full record

ArticleRSC advances2019

A novel method for the preparation of solvent-free, microwave-assisted and nitrogen-doped carbon dots as fluorescent probes for chromium(vi) detection and bioimaging.

Meng Cao, Yong Li, Yunze Zhao, Chongyang Shen, Hongyan Zhang, Yuanfang Huang

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Green Synthesis of Nitrogen-Doped Carbon Dots fromSensors (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Carbon dots derived fromJournal of pharmaceutical analysis · 2022
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meng CaoCollege of Resources and Environment Sciences, China Agricultural University Beijing 100193 China yfhuang@cau.edu.cn.
Yong LiCollege of Resources and Environment Sciences, China Agricultural University Beijing 100193 China yfhuang@cau.edu.cn.
Yunze ZhaoCollege of Resources and Environment Sciences, China Agricultural University Beijing 100193 China yfhuang@cau.edu.cn.
Chongyang ShenCollege of Resources and Environment Sciences, China Agricultural University Beijing 100193 China yfhuang@cau.edu.cn.ORCID https://orcid.org/0000-0002-2517-3472
Hongyan ZhangCollege of Science, China Agricultural University Beijing 100193 China.ORCID https://orcid.org/0000-0003-1795-5172
Yuanfang HuangCollege of Resources and Environment Sciences, China Agricultural University Beijing 100193 China yfhuang@cau.edu.cn.ORCID https://orcid.org/0000-0002-8839-9655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromium(vi) [Cr(vi)] has been shown to be toxic to organisms due to its mutagenicity and carcinogenicity. Therefore, the exploitation of probes with low toxicity and high sensitivity for Cr(vi) detection is needed. In this study, a one-step, solvent-free, and microwave-assisted method was developed for the preparation of nitrogen-doped carbon dots (N-CDs). The reaction could be finished in just three minutes, and the yield of the dots could reach 58.5%; the as-prepared N-CDs exhibited excellent water solubility, emitted bright cyan fluorescence with a high quantum yield of 38.88%, and possessed excitation- and concentration-dependent characteristics. The N-CDs could be effectively applied to Cr(vi) detection with a linear range of 1-100 μM, and the detection limit could be as low as 0.12 μM. The quenching mechanism was responsible for the inner filter effect, and the quenched fluorescence could be recovered with a linear range of 5-100 μM by the addition of ascorbic acid. We showed that the fluorescent probes could even be employed for the detection of Cr(vi) in river water and for bio-imaging because of their nearly zero cytotoxicity; this showed the potential application of these probes in ion detection and cellular bioimaging. Herein, we have provided an effective strategy to rapidly obtain high-quality N-CDs using a solid-phase microwave method, and the as-prepared N-CDs exhibit various potential applications in environmental and biological fields.

Identifiers

PMID35518661
PMCPMC9061421

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.