Evidence map›Paper›PMID 35518599›Full record

ArticleRSC advances2020

Synthesis and anti-osteoporosis activity of novel Teriparatide glycosylation derivatives.

Nan Wang, Jingyang Li, Hui Song, Chao Liu, Honggang Hu, Hongli Liao, Wei Cong

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nan WangInstitute of Translational Medicine, Shanghai University Shanghai China viviencong@shu.edu.cn.ORCID https://orcid.org/0000-0002-1011-4509
Jingyang LiDepartment of Pediatric Respiratory Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Hui SongInstitute of Translational Medicine, Shanghai University Shanghai China viviencong@shu.edu.cn.
Chao LiuInstitute of Translational Medicine, Shanghai University Shanghai China viviencong@shu.edu.cn.ORCID https://orcid.org/0000-0001-9176-7343
Honggang HuInstitute of Translational Medicine, Shanghai University Shanghai China viviencong@shu.edu.cn.ORCID https://orcid.org/0000-0003-0577-3021
Hongli LiaoSchool of Pharmacy, Chengdu Medical College Chengdu China liaohl213@126.com.ORCID https://orcid.org/0000-0001-5958-1506
Wei CongInstitute of Translational Medicine, Shanghai University Shanghai China viviencong@shu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a metabolic bone disease that is characterized by low bone mass and micro-architectural deterioration of bones. The mechanism underlying this disease implicates an imbalance between bone resorption and bone remodeling. In 2002, the US Food and Drug Administration (FDA) approved Teriparatide for the treatment of osteoporosis, and so far, this compound is the only permitted osteoanabolic. However, as a structurally flexible linear peptide, this drug may be further optimized. In this study, we develop a series of novel

Identifiers

PMID35518599
PMCPMC9055339

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.