Evidence map›Paper›PMID 35518395›Full record

ArticleRSC advances2020

pH-Sensitive magnetite mesoporous silica nanocomposites for controlled drug delivery and hyperthermia.

Hasan Keshavarz, Alireza Khavandi, Somaye Alamolhoda, M Reza Naimi-Jamal

Abstract read
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In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Mesoporous FeRSC advances · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hasan KeshavarzSchool of Metallurgy and Materials Engineering, Iran University of Science and Technology P.O. Box 13114-16846 Tehran Iran alamolhoda@iust.ac.ir +98 2177240480 +98 2173228885.ORCID https://orcid.org/0000-0002-7970-0098
Alireza KhavandiSchool of Metallurgy and Materials Engineering, Iran University of Science and Technology P.O. Box 13114-16846 Tehran Iran alamolhoda@iust.ac.ir +98 2177240480 +98 2173228885.
Somaye AlamolhodaSchool of Metallurgy and Materials Engineering, Iran University of Science and Technology P.O. Box 13114-16846 Tehran Iran alamolhoda@iust.ac.ir +98 2177240480 +98 2173228885.ORCID https://orcid.org/0000-0003-3561-5745
M Reza Naimi-JamalResearch Laboratory of Green Organic Synthesis & Polymers, Department of Chemistry, Iran University of Science and Technology P.O. Box 13114-16846 Tehran Iran.ORCID https://orcid.org/0000-0002-8305-7234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical applications, chemotherapy and hyperthermia are commonly used together. To achieve this, we synthesized multifunctional magnetite mesoporous silica nanoparticles (MMSNs) coated with a chitosan hydrogel. pH-Responsive chitosan hydrogels (cross-linked glutaraldehyde) were used to cover mesoporous silica pores. The infrared spectroscopy (FT-IR) and electron microscopy images (SEM and TEM) confirm that a hydrogel layer and a silica shell were formed. By applying alternating magnetic fields (AMF) to nanogels, heat generation (43 °C) occurred within a short time. The drug release (tamoxifen) of nanogels was studied for 72 h at different pH and temperatures. Drug release at pH 7.4/

Identifiers

PMID35518395
PMCPMC9057345

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.