ArticleRSC advances2020
The 1α-hydroxy-A-rings of norditerpenoid alkaloids are twisted-boat conformers.
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Synthesis and Antagonist Activity of Methyllycaconitine Analogues on Human α7 Nicotinic Acetylcholine Receptors.ACS bio & med chem Au · 2023Article
- Effect of Position 1 Substituent and Configuration on APCI-MS Fragmentation of Norditerpenoid Alkaloids Including 1-ACS omega · 2022Article
- Poisonous Piperidine Plants and the Biodiversity of Norditerpenoid Alkaloids for Leads in Drug Discovery: Experimental Aspects.International journal of molecular sciences · 2022Review
- CRSC advances · 2021Review
- TheACS omega · 2021Article
- Impacts of Steric Compression, Protonation, and Intramolecular Hydrogen Bonding on theACS omega · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The skeletal conformations of naturally occurring norditerpenoid alkaloids fix their substituent functional groups in space, thereby directing their bioactivities. Solution conformations of the A-rings of 4 selected norditerpenoid alkaloid free bases: mesaconitine, karacoline (karakoline), condelphine, and neoline (bullatine B), were analysed by NMR spectroscopy and single-crystal X-ray crystallography. They adopt twisted-chair, twisted-boat, twisted-boat, twisted-boat conformations, respectively. That the A-ring is stabilised in a boat conformer by an intramolecular H-bond from 1α-OH to the
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Registered trials
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