Evidence map›Paper›PMID 35518160›Full record

ArticleRSC advances2020

Inhibition of SARS-CoV-2 main protease by phenolic compounds from

Fatma M Abd El-Mordy, Mohamed M El-Hamouly, Magda T Ibrahim, Gehad Abd El-Rheem, Omar M Aly, Adel M Abd El-Kader, Khayrya A Youssif, Usama Ramadan Abdelmohsen

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Inhibition of the main protease of SARS-CoV-2 (MComputational and structural biotechnology journal · 2022
    Review
  8. Article
  9. Metabolites Profiling ofInternational journal of analytical chemistry · 2022
    Article
  10. Review
  11. Article
  12. Antiviral activities of flavonoids.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatma M Abd El-MordyDepartment of Pharmacognosy, Faculty of Pharmacy (Girls), Al-Azhar University 11754 Cairo Egypt.ORCID https://orcid.org/0000-0002-5554-2064
Mohamed M El-HamoulyDepartment of Pharmacognosy, Faculty of Pharmacy (Boys), Al-Azhar University 11371 Cairo Egypt.
Magda T IbrahimDepartment of Pharmacognosy, Faculty of Pharmacy, Sinai University 41636 Kantara Branch Egypt.
Gehad Abd El-RheemDepartment of Pharmacology, National Research Centre 12622 Giza Egypt.
Omar M AlyDepartment of Medicinal Chemistry, Faculty of Pharmacy, Minia University 61519 Minia Egypt.
Adel M Abd El-KaderDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University 61111 Minia Egypt Usama.ramadan@mu.edu.eg.
Khayrya A YoussifDepartment of Pharmacognosy, Faculty of Pharmacy, Modern University for Technology and Information Cairo Egypt.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University 61111 Minia Egypt Usama.ramadan@mu.edu.eg.ORCID https://orcid.org/0000-0002-1014-6922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 is a novel coronavirus that was first identified during the outbreak in Wuhan, China in 2019. It is an acute respiratory illness that can transfer among human beings. Natural products can provide a rich resource for novel antiviral drugs. They can interfere with viral proteins such as viral proteases, polymerases, and entry proteins. Several naturally occurring flavonoids were reported to have antiviral activity against different types of RNA and DNA viruses. A methanolic extract of

Identifiers

PMID35518160
PMCPMC9056568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.