Evidence map›Paper›PMID 35518073›Full record

ArticleRSC advances2019

Pharmacokinetic profile and metabolite identification of bornyl caffeate and caffeic acid in rats by high performance liquid chromatography coupled with mass spectrometry.

Baimei Shi, Lingjian Yang, Tian Gao, Cuicui Ma, Qiannan Li, Yefei Nan, Shixiang Wang, Chaoni Xiao, Pu Jia, Xiaohui Zheng

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Novel Antioxidant Caffeate Esters of Black Locust (Plants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Discovery of quality markers ofFrontiers in pharmacology · 2024
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Baimei ShiKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Lingjian YangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Tian GaoKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Cuicui MaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Qiannan LiKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Yefei NanKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Shixiang WangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Chaoni XiaoKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Pu JiaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.
Xiaohui ZhengKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education/College of Life Science, Northwest University 195# Mail Box, No. 229 Northern Taibai Road Xi'an 710069 P. R. China Jiapu77@126.com zhengxh@nwu.edu.cn +86-29-88302686 +86-29-88302686.ORCID https://orcid.org/0000-0002-9967-9302
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bornyl caffeate was initially discovered as a bioactive compound in medicinal plants. Despite the promising pharmacological activities including anti-tumor and antibacterial activities, the pharmacokinetics of the compound remain open. This work developed a high performance liquid chromatography-tandem mass spectrometric method for the determination of bornyl caffeate and caffeic acid (major metabolite and a main unit of bornyl caffeate)

Identifiers

PMID35518073
PMCPMC9060532
OpenAlexW2912832579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.