Evidence map›Paper›PMID 35517953›Full record

ArticleRSC advances2020

Quantitative analysis of hydrogen and chalcogen bonds in two pyrimidine-5-carbonitrile derivatives, potential DHFR inhibitors: an integrated crystallographic and theoretical study.

Lamya H Al-Wahaibi, Kushumita Chakraborty, Nora H Al-Shaalan, Mohamed Yehya Annavi Syed Majeed, Olivier Blacque, Aamal A Al-Mutairi, Ali A El-Emam, M Judith Percino, Subbiah Thamotharan

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 9 countries.

Lamya H Al-WahaibiDepartment of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University Riyadh 11671 Saudi Arabia.
Kushumita ChakrabortyBiomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University Thanjavur-613401 India thamu@scbt.sastra.edu.
Nora H Al-ShaalanDepartment of Chemistry, College of Sciences, Princess Nourah Bint Abdulrahman University Riyadh 11671 Saudi Arabia.ORCID https://orcid.org/0000-0002-5285-2155
Mohamed Yehya Annavi Syed MajeedBiomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University Thanjavur-613401 India thamu@scbt.sastra.edu.
Olivier BlacqueDepartment of Chemistry, University of Zürich Winterthurerstrasse 190 8057 Zürich Switzerland.ORCID https://orcid.org/0000-0001-9857-4042
Aamal A Al-MutairiDepartment of Chemistry, College of Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh 11671 Saudi Arabia.
Ali A El-EmamDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University Mansoura 35516 Egypt.
M Judith PercinoUnidad de Polímeros y Electrónica Orgánica, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla Val3-Ecocampus Valsequillo, Independencia O2 Sur 50, San Pedro Zacachimalpa Puebla-C.P.72960 Mexico.ORCID https://orcid.org/0000-0003-1610-7155
Subbiah ThamotharanBiomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University Thanjavur-613401 India thamu@scbt.sastra.edu.ORCID https://orcid.org/0000-0003-2758-6649
Tamil University · INPrincess Nourah bint Abdulrahman University · SAImam Mohammad ibn Saud Islamic University · SAInstituto de Ciencia y Tecnología de Polímeros · ESMansoura University · EGUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two potential bioactive pyrimidine-5-carbonitrile derivatives have been synthesized and characterized by spectroscopic techniques (

Identifiers

PMID35517953
PMCPMC9057057
OpenAlexW3092380066

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.