Evidence map›Paper›PMID 35517886›Full record

ReviewAdvanced pharmaceutical bulletin2022

Medicinal Plants with Potential Inhibitory Bioactive Compounds against Coronaviruses.

Olutayo Ademola Adeleye, Oluyemisi Adebowale Bamiro, Lateef Gbenga Bakre, Florence Olubola Odeleye, Modupe Nofisat Adebowale, Olufemi Lionel Okunye, Mariam Adeola Sodeinde, Adannaya Charity Adebona, Farid Menaa

Abstract readReview
In one paragraph

Review in Advanced pharmaceutical bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Immunization against Medically Important Human Coronaviruses of Public Health Concern.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  8. Antitumor and Phytochemical Properties ofMolecules (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olutayo Ademola AdeleyeDepartment of Pharmaceutics and Pharmaceutical Technology, Federal University Oye-Ekiti, Ekiti State, Nigeria.ORCID https://orcid.org/0000-0001-8716-4064
Oluyemisi Adebowale BamiroDepartment of Pharmaceutics and Pharmaceutical Technology, Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.
Lateef Gbenga BakreDepartment of Pharmaceutics and Pharmaceutical Technology, Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.ORCID https://orcid.org/0000-0003-1222-1057
Florence Olubola OdeleyeDepartment of Pharmaceutical Microbiology,Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.ORCID https://orcid.org/0000-0002-1783-1463
Modupe Nofisat AdebowaleDepartment of Pharmacognosy Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.
Olufemi Lionel OkunyeDepartment of Pharmaceutical Microbiology,Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.
Mariam Adeola SodeindeDepartment of Pharmacognosy Olabisi Onabanjo University, Ago Iwoye, Ogun State, Nigeria.
Adannaya Charity AdebonaDepartment of Pharmaceutics and Pharmaceutical Technology, Federal University Oye-Ekiti, Ekiti State, Nigeria.
Farid MenaaDepartment of Translational Nanomedicine and Advanced Technologies California Innovations Corporation, San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0002-0258-7322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plant is a major source of drug discovery for disease management. Over 85% of the population in Asia and in the Middle East use herbal medicine for disease management such as severe acute respiratory syndrome (SARS) caused by coronavirus. Infection from coronavirus is initiated by entry of the virus into a susceptible host cell. The two human coronaviruses of public health importance two decades ago were SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV) and now SARS-CoV-2. These three viruses belong to the same class of beta coronavirus and are somewhat similar in genome sequencing, life cycle, mode of entry into a host, mode of transmission and clinical manifestations. This review identified twenty medicinal plants with potential inhibitory bioactive compounds from natural sources that are active against coronaviruses that could be developed into various drug delivery systems. It also highlighted several evidences to show that medicinal plant used in the treatment of SARSCoV may offer some sort of relief from the burden of coronavirus disease 2019 (COVID-19) pandemic. Since there is no specific treatment for COVID-19 yet, the search for medicinal plants with inhibitory bioactive compounds against coronavirus could be the long awaited breakthrough scientists have been searching to change the narratives of COVID-19 pandemic.

Indexed as

Bioactive compoundsCoronavirusMedicinal plantSARS-CoV

Identifiers

PMID35517886
PMCPMC9012928

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.