Evidence map›Paper›PMID 35517709›Full record

ArticleRSC advances2019

Optimization of makerspace microfabrication techniques and materials for the realization of planar, 3D printed microelectrode arrays in under four days.

Avra Kundu, Crystal Nattoo, Sarah Fremgen, Sandra Springer, Tariq Ausaf, Swaminathan Rajaraman

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026
    Review
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  4. Article
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  6. Review
  7. Rapid Makerspace Microfabrication and Characterization of 3D Microelectrode Arrays (3D MEAs) for Organ-on-a-Chip Models.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Avra KunduNanoScience Technology Center (NSTC), University of Central Florida Research I, Office 237, 4353 Scorpius Street Orlando FL 32816-0120 USA Swaminathan.Rajaraman@ucf.edu +1-407-823-4339.ORCID https://orcid.org/0000-0003-1892-903X
Crystal NattooDepartment of Electrical and Computer Engineering, University of Miami Coral Gables FL 33146 USA.ORCID https://orcid.org/0000-0001-9045-5575
Sarah FremgenNanoScience Technology Center (NSTC), University of Central Florida Research I, Office 237, 4353 Scorpius Street Orlando FL 32816-0120 USA Swaminathan.Rajaraman@ucf.edu +1-407-823-4339.
Sandra SpringerNanoScience Technology Center (NSTC), University of Central Florida Research I, Office 237, 4353 Scorpius Street Orlando FL 32816-0120 USA Swaminathan.Rajaraman@ucf.edu +1-407-823-4339.
Tariq AusafNanoScience Technology Center (NSTC), University of Central Florida Research I, Office 237, 4353 Scorpius Street Orlando FL 32816-0120 USA Swaminathan.Rajaraman@ucf.edu +1-407-823-4339.
Swaminathan RajaramanNanoScience Technology Center (NSTC), University of Central Florida Research I, Office 237, 4353 Scorpius Street Orlando FL 32816-0120 USA Swaminathan.Rajaraman@ucf.edu +1-407-823-4339.
University of Central Florida · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional two-dimensional microelectrode arrays (2D MEAs) in the market involve long manufacturing timeframes, have cleanroom requirements, and need to be assembled from multiple parts to obtain the final packaged device. For MEAs to be "used and tossed", manufacturing has to be moved from the cleanroom to makerspaces. In order to enable makerspace fabricated MEAs comparable to conventional MEAs, the microfabrication processes must be optimized to have similar electrical properties along with biocompatibility and number of recording sites. This work presents a makerspace microfabricated 2D MEA having electrode densities up to a commercially popular 8 × 8 array, all fabricated under four days. Additive manufacturing-based realization of the MEA devices provides immense flexibility in terms of meeting distinct design requirements. A unique non-planar MEA having meso-scale electrodes on the top side of a chip transitioning to traces onto the bottom side through electrical vias is presented in this work. This allows for (a) monolithic integration of a culture well for devices having up to a 6 × 6 MEA array, (b) selective electroplating of the meso-scale electrodes (500 μm diameter) defined by silver ink casting followed by pulsed electroplating of gold or platinum without any masking procedure, (c) casting of a uniform and planar insulation layer

Identifiers

PMID35517709
PMCPMC9062012
OpenAlexW2920873524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.