Evidence map›Paper›PMID 35517697›Full record

ArticleRSC advances2019

An integrated microchannel biosensor platform to analyse low density lactate metabolism in HepG2 cells

Shengli Mi, Jingjing Xia, Yuanyuan Xu, Zhichang Du, Wei Sun

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Shengli MiGraduate School at Shenzhen, Tsinghua University Shenzhen 51805 P. R. China.ORCID https://orcid.org/0000-0002-4787-0674
Jingjing XiaGraduate School at Shenzhen, Tsinghua University Shenzhen 51805 P. R. China.ORCID https://orcid.org/0000-0002-1326-6882
Yuanyuan XuGraduate School at Shenzhen, Tsinghua University Shenzhen 51805 P. R. China.
Zhichang DuGraduate School at Shenzhen, Tsinghua University Shenzhen 51805 P. R. China.
Wei SunGraduate School at Shenzhen, Tsinghua University Shenzhen 51805 P. R. China.
University Town of Shenzhen · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we developed an electrochemical microchannel biosensor platform to analyse lactate metabolism in cells. This biosensor platform was fabricated by photolithography, thin-film deposition and microfluidic technology. A kind of functional biomaterial was prepared by mixing lactate oxidase, single-walled carbon nanotubes and chitosan, and platinum as working and blank electrodes of the biosensor was modified by a thin Prussian blue layer. The lactate biosensor was obtained by dropping functional biomaterials on the electrode. The results demonstrated that the sensitivity of the electrochemical biosensor was up to 567 nA mM

Identifiers

PMID35517697
PMCPMC9062021
OpenAlexW2925177178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.