Evidence map›Paper›PMID 35517674›Full record

ArticleRSC advances2019

Luminescent bis(benzo[

Lavanya Thilak Babu, Gajanan Raosaheb Jadhav, Priyankar Paira

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lavanya Thilak BabuDepartment of Chemistry, School of Advanced Sciences, Vellore Institute of Technology Vellore-632014 Tamilnadu India priyankar.paira@vit.ac.in +91-416-2243092 +91-416-2243091.
Gajanan Raosaheb JadhavDepartment of Chemistry, School of Advanced Sciences, Vellore Institute of Technology Vellore-632014 Tamilnadu India priyankar.paira@vit.ac.in +91-416-2243092 +91-416-2243091.
Priyankar PairaDepartment of Chemistry, School of Advanced Sciences, Vellore Institute of Technology Vellore-632014 Tamilnadu India priyankar.paira@vit.ac.in +91-416-2243092 +91-416-2243091.ORCID https://orcid.org/0000-0003-1698-4895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of quinoxaline-2-hydroxyphenylbenzothiazole scaffolds were synthesized and characterized using NMR, UV, fluorescence spectroscopy and LCMS. These newly synthesized compounds were found to be cytotoxic in human epithelioid cervix carcinoma (HeLa) and human colon cancer cell lines (Caco-2). Selectivity of the compounds 7e and 7g are more than 9 fold higher in Caco-2 cells with respect to the normal cell line HEK-293. The most fluorescent compound 7e has displayed high cytoselectivity, significant cellular uptake in HeLa cells and strong binding efficacy with DNA and BSA. The most potent compound 7g has primarily classified as BCS class 4 and BDDCS class 4.

Identifiers

PMID35517674
PMCPMC9061853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.