Evidence map›Paper›PMID 35517533›Full record

ArticleRSC advances2020

Deuteration

Markus Laube, Cemena Gassner, Christin Neuber, Robert Wodtke, Martin Ullrich, Cathleen Haase-Kohn, Reik Löser, Martin Köckerling, Klaus Kopka, Torsten Kniess and 2 more

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. A Ni-Mediated Cross-Coupling Approach to DeuteratedJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Preclinical evaluation of anEJNMMI radiopharmacy and chemistry · 2024
    Article
  4. Preparation ofPharmaceutics · 2023
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Markus LaubeHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0003-4916-3794
Cemena GassnerHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.
Christin NeuberHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0002-0646-5808
Robert WodtkeHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0001-7462-7111
Martin UllrichHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0001-6104-6676
Cathleen Haase-KohnHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0002-5032-5095
Reik LöserHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0003-1531-7601
Martin KöckerlingUniversity of Rostock, Institute of Chemistry, Department of Inorganic Solid State Chemistry Albert-Einstein-Str. 3a D-18059 Rostock Germany.ORCID https://orcid.org/0000-0001-7666-6990
Klaus KopkaHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0003-4846-1271
Torsten KniessHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0002-4107-3455
Evamarie Hey-HawkinsLeipzig University, Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry Johannisallee 29 D-04103 Leipzig Germany.ORCID https://orcid.org/0000-0003-4267-0603
Jens PietzschHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Bautzner Landstrasse 400 01328 Dresden Germany m.laube@hzdr.de j.pietzsch@hzdr.de.ORCID https://orcid.org/0000-0002-1610-1493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inducible isoenzyme cyclooxygenase-2 (COX-2) is closely associated with chemo-/radioresistance and poor prognosis of solid tumors. Therefore, COX-2 represents an attractive target for functional characterization of tumors by positron emission tomography (PET). In this study, the celecoxib derivative 3-([

Identifiers

PMID35517533
PMCPMC9057277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.