Evidence map›Paper›PMID 35517527›Full record

ArticleRSC advances2020

Bifunctional thiosquaramide catalyzed asymmetric reduction of dihydro-β-carbolines and enantioselective synthesis of (-)-coerulescine and (-)-horsfiline by oxidative rearrangement.

Manda Sathish, Fabiane M Nachtigall, Leonardo S Santos

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manda SathishLaboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca Casilla 747 3460000 Talca Chile lssantos@utalca.cl.
Fabiane M NachtigallInstituto de Ciencias Químicas Aplicadas, Universidad Autónoma de Chile Talca 3467987 Chile.
Leonardo S SantosLaboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca Casilla 747 3460000 Talca Chile lssantos@utalca.cl.ORCID https://orcid.org/0000-0002-1697-4200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetrahydro-β-carboline (THBC) is a tricyclic ring system that can be found in a large number of bioactive alkaloids. Herein, we report a simple and efficient method for the synthesis of enantiopure THBCs through a chiral thiosquaramide (11b) catalyzed imine reduction of dihydro-β-carbolines (17a-f). The

Identifiers

PMID35517527
PMCPMC9057260

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.