Evidence map›Paper›PMID 35517137›Full record

ArticleRSC advances2020

Multilayered composite-coated ionically crosslinked food-grade hydrogel beads generated from algal alginate for controlled and sustained release of bioactive compounds.

Wing-Fu Lai, Eric Wong, Wing-Tak Wong

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wing-Fu LaiDepartment of Applied Biology and Chemical Technology, Hong Kong Polytechnic University Hong Kong Special Administrative Region China rori0610@graduate.hku.hk.ORCID https://orcid.org/0000-0003-0585-6396
Eric WongDepartment of Applied Biology and Chemical Technology, Hong Kong Polytechnic University Hong Kong Special Administrative Region China rori0610@graduate.hku.hk.
Wing-Tak WongDepartment of Applied Biology and Chemical Technology, Hong Kong Polytechnic University Hong Kong Special Administrative Region China rori0610@graduate.hku.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels have gained interest as sustained-release matrices partly because of their high biocompatibility and ease of preparation. Their wide application has, however, been limited by their poor mechanical strength and their lack of tunability in the performance of bioactive agent delivery. By using the lake substratum as a gel property modifier, in combination with the use of the surface coating approach and the ionic gelation technique, hydrogel beads are generated from algal alginate for controlled and sustained release of bioactive compounds. Both the acute and chronic toxicity of the beads are found to be negligible in 3T3 fibroblasts. The capacity of the beads in retaining the activity of the loaded agent is verified by the negligible change in the action of the loaded compound on foodborne bacteria (

Identifiers

PMID35517137
PMCPMC9058451

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.