Evidence map›Paper›PMID 35517096›Full record

ArticleRSC advances2020

Development of an on-chip sample injection system with a 6-port valve incorporated in a microchip.

Kazuhiro Morioka, Hina Sato, Kenji Morita, Hemmi Akihide, Hizuru Nakajima, Atsushi Shoji, Akio Yanagida

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. The usage of color coordinates preserved in microscopic image for elucidation on chemical behavior in confined micro-/nano-spaces.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Kazuhiro MoriokaDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan kmorioka@toyaku.ac.jp.ORCID https://orcid.org/0000-0002-7149-121X
Hina SatoDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan kmorioka@toyaku.ac.jp.
Kenji MoritaDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan kmorioka@toyaku.ac.jp.
Hemmi AkihideMebius Advanced Technology Ltd. 3-31-6 Nishiogi-kita Suginami-ku Tokyo 167-0042 Japan.ORCID https://orcid.org/0000-0002-1452-5890
Hizuru NakajimaDepartment of Applied Chemistry, Graduate School of Urban Environmental Science, Tokyo Metropolitan University 1-1 Minami-ohsawa Hachioji Tokyo 192-0397 Japan.
Atsushi ShojiDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan kmorioka@toyaku.ac.jp.
Akio YanagidaDepartment of Biomedical Analysis, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan kmorioka@toyaku.ac.jp.
Tokyo University of Pharmacy and Life Sciences · JPTokyo Metropolitan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro-flow-injection analysis (μFIA) is amenable to high-throughput systems with lower consumption of sample and reagent volumes. On-chip sample injection methods are important to prevent reduced analytical performance associated with dead volumes and diffusion of sample solutions. In this study, we have developed an on-chip sample injection system with a small-sized 6-port valve incorporated on a microchip. The valve is made with a 3D printer and is a simple structure that can be easily operated manually. A sample solution in a loading channel can be injected by switching the valve from the load to injection position. Sample injection tests using resorufin solutions revealed that samples can be injected below 100 μL min

Identifiers

PMID35517096
PMCPMC9056900
OpenAlexW3089905192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.