Evidence map›Paper›PMID 35516781›Full record

ArticleRSC advances2020

Zn(ii)2,9-dimethyl-1,10-phenanthroline stimulates cultured bovine aortic endothelial cell proliferation.

Takehiro Nakamura, Eiko Yoshida, Takato Hara, Tomoya Fujie, Chika Yamamoto, Yasuyuki Fujiwara, Fumihiko Ogata, Naohito Kawasaki, Ryo Takita, Masanobu Uchiyama and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2023
    Article
  3. Reply to Suresh.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Takehiro NakamuraFaculty of Pharmaceutical Sciences, Tokyo University of Science 2641 Yamazaki Noda 278-8510 Japan.
Eiko YoshidaFaculty of Pharmaceutical Sciences, Tokyo University of Science 2641 Yamazaki Noda 278-8510 Japan.ORCID https://orcid.org/0000-0001-5957-7697
Takato HaraFaculty of Pharmaceutical Sciences, Toho University 2-2-1 Miyama Funabashi 274-8510 Japan.
Tomoya FujieFaculty of Pharmaceutical Sciences, Toho University 2-2-1 Miyama Funabashi 274-8510 Japan.
Chika YamamotoFaculty of Pharmaceutical Sciences, Toho University 2-2-1 Miyama Funabashi 274-8510 Japan.
Yasuyuki FujiwaraSchool of Pharmacy, Tokyo University of Pharmacy and Life Sciences 1432-1 Horinouchi Hachioji 192-0392 Japan.ORCID https://orcid.org/0000-0003-0028-0658
Fumihiko OgataFaculty of Pharmacy, Kindai University 3-4-1 Kowakae Higashi-Osaka 577-8502 Japan.
Naohito KawasakiFaculty of Pharmacy, Kindai University 3-4-1 Kowakae Higashi-Osaka 577-8502 Japan.
Ryo TakitaGraduate School of Pharmaceutical Sciences, The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-0033 Japan.ORCID https://orcid.org/0000-0003-4104-9890
Masanobu UchiyamaGraduate School of Pharmaceutical Sciences, The University of Tokyo 7-3-1 Hongo Bunkyo-ku 113-0033 Japan.ORCID https://orcid.org/0000-0001-6385-5944
Toshiyuki KajiFaculty of Pharmaceutical Sciences, Tokyo University of Science 2641 Yamazaki Noda 278-8510 Japan.ORCID https://orcid.org/0000-0002-7393-2656
Toho University · JPTokyo University of Science · JPBunkyo University · JPHigashi Osaka City General Hospital · JPTokyo University of Pharmacy and Life Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial cells cover the luminal surface of blood vessels in a monolayer. Proliferation of these cells is crucial for the repair of damaged endothelial monolayers. In the present study, we identified a zinc complex, Zn(ii)2,9-dimethyl-1,10-phenanthroline (Zn-12), that stimulates the proliferation of bovine aortic endothelial cells in a culture system. No such stimulatory activity was observed for the ligand alone or in combination with other metals; however, the ligand combined with iron weakly stimulated the proliferation, as evidenced by the [

Identifiers

PMID35516781
PMCPMC9057965
OpenAlexW3108771974

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.