Evidence map›Paper›PMID 35516759›Full record

ArticleRSC advances2020

Effects of the surface polarity of nanomaterials on their interaction with complement protein gC1q.

Shuai Wang, Xinwen Ou, Yanee Wutthinitikornkit, Ming Yi, Jingyuan Li

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuai WangCollege of Informatics, Huazhong Agricultural University Wuhan 430070 China.
Xinwen OuDepartment of Physics, Zhejiang University Hangzhou 310027 China jingyuanli@zju.edu.cn.
Yanee WutthinitikornkitDepartment of Physics, Zhejiang University Hangzhou 310027 China jingyuanli@zju.edu.cn.
Ming YiCollege of Informatics, Huazhong Agricultural University Wuhan 430070 China.
Jingyuan LiDepartment of Physics, Zhejiang University Hangzhou 310027 China jingyuanli@zju.edu.cn.ORCID https://orcid.org/0000-0003-2926-1864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are increasing studies about the biocompatibility of nanomaterials (NMs) as their applications in biomedicine become more widespread. The biocompatibility of NMs involves the recognition by the immune system including complement protein gC1q. In this work, the interaction of graphene oxide (GO) and self-assembled monolayer (SAM)-coated gold (111) surface with gC1q was studied by molecular dynamics (MD) simulations. The impacts of surface polarity of GO on its interaction with gC1q and the possible immune response were discussed by comparing the binding behavior of gC1q to the GO sheets with different oxidation degrees (

Identifiers

PMID35516759
PMCPMC9057849

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.