Evidence map›Paper›PMID 35516581›Full record

ArticleRSC advances2020

Activatable superparamagnetic iron oxide nanoparticles scavenge reactive oxygen species in macrophages and endothelial cells.

Chukwuazam Nwasike, Eunsoo Yoo, Erin Purr, Amber L Doiron

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. [Research progress on the effect of iron oxide nanoparticles in macrophage polarization].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chukwuazam NwasikeDepartment of Biomedical Engineering, Binghamton University (SUNY) Binghamton NY 13902 USA.ORCID https://orcid.org/0000-0001-7685-3817
Eunsoo YooDepartment of Biomedical Engineering, Binghamton University (SUNY) Binghamton NY 13902 USA.
Erin PurrDepartment of Biomedical Engineering, Binghamton University (SUNY) Binghamton NY 13902 USA.
Amber L DoironDepartment of Electrical and Biomedical Engineering, University of Vermont Burlington VT 05405 USA amber.doiron@uvm.edu +1-802-656-3382.ORCID https://orcid.org/0000-0002-6963-0989
Binghamton University · USUniversity of Vermont · US

Funding

Iron Oxide Based Polymer Nanocomplex for Functional Detection of AtherosclerosisR21EB017504 · NIBIB · STATE UNIVERSITY OF NY,BINGHAMTON · PI DOIRON, AMBER L, FISHER, OMAR Z · 2013 to 2014
$413k
NIBIB NIH HHS R21 EB017504
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are key markers of inflammation, with varying levels of superoxide indicating the degree of inflammation. Inflammatory diseases remain the leading cause of death in the developed world. Previously, we showed that interpolymer complexed superparamagnetic iron oxide nanoparticles (IPC-SPIOs) are capable of decomplexing and activating T

Identifiers

PMID35516581
PMCPMC9057763
OpenAlexW3098531536

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.