Evidence map›Paper›PMID 35516575›Full record

ReviewRSC advances2020

Photodynamic diagnosis and photodynamic therapy of colorectal cancer

Nokuphila Winifred Nompumelelo Simelane, Cherie Ann Kruger, Heidi Abrahamse

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

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  19. Phosphorescent Metal Halide Nanoclusters for Tunable Photodynamic Therapy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 3 countries.

Nokuphila Winifred Nompumelelo SimelaneLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein Johannesburg 2028 South Africa habrahamse@uj.ac.za +27 11 559 6550.ORCID https://orcid.org/0000-0003-3368-7147
Cherie Ann KrugerLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein Johannesburg 2028 South Africa habrahamse@uj.ac.za +27 11 559 6550.ORCID https://orcid.org/0000-0002-4556-9132
Heidi AbrahamseLaser Research Centre, Faculty of Health Sciences, University of Johannesburg P.O. Box 17011, Doornfontein Johannesburg 2028 South Africa habrahamse@uj.ac.za +27 11 559 6550.ORCID https://orcid.org/0000-0001-5002-827X
University of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a global challenge to eradicate. Early diagnosis and treatment strategies with ideal advantages, such as high tumor selectivity and negligible adverse effects, are significant, since they can result in precise diagnosis and treatment to reduce the overall incidence of CRC. The photodynamic approach for the detection and therapeutic treatment of cancer is a promising novel strategy in comparison to conventional treatments. Photodynamic diagnosis (PDD) is a diagnostic modality that involves the emission of light-induced excitation fluorescence to enhance early detection, without tumor destruction, after photosensitizer exposure to blue light. Photodynamic therapy (PDT) is a photochemistry-based approach that is rapidly progressing to solve the limitations of standard CRC treatments. PDT involves the interaction of a photosensitizer, tissue oxygen, and red light, which forms reactive oxygen species and radicals to elicit localized cancer cell death. This review discusses conventional CRC diagnostic and treatment methods, with their limitations, in comparison to the newly evolving

Identifiers

PMID35516575
PMCPMC9058000
OpenAlexW3102080619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.