Evidence map›Paper›PMID 35516361›Full record

ArticleRSC advances2019

Biological reduction of nitroimidazole-functionalized gold nanorods for photoacoustic imaging of tumor hypoxia.

Yui Umehara, Toki Kageyama, Aoi Son, Yu Kimura, Teruyuki Kondo, Kazuhito Tanabe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yui UmeharaDepartment of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 615-8510 Japan teruyuki@scl.kyoto-u.ac.jp +81-75-383-2504 +81-75-383-7055.
Toki KageyamaDepartment of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 615-8510 Japan teruyuki@scl.kyoto-u.ac.jp +81-75-383-2504 +81-75-383-7055.
Aoi SonDepartment of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 615-8510 Japan teruyuki@scl.kyoto-u.ac.jp +81-75-383-2504 +81-75-383-7055.
Yu KimuraDepartment of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 615-8510 Japan teruyuki@scl.kyoto-u.ac.jp +81-75-383-2504 +81-75-383-7055.
Teruyuki KondoDepartment of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University Nishikyo-ku Kyoto 615-8510 Japan teruyuki@scl.kyoto-u.ac.jp +81-75-383-2504 +81-75-383-7055.ORCID https://orcid.org/0000-0003-1213-2337
Kazuhito TanabeDepartment of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin University 5-10-1 Fuchinobe, Chuo-ku Sagamihara 252-5258 Japan tanabe.kazuhito@chem.aoyama.ac.jp +81-42-759-6493 +81-42-759-6229.ORCID https://orcid.org/0000-0003-2440-2293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-selective accumulation of gold nanorods (GNR) has been demonstrated for visualization of tumor hypoxia by photoacoustic imaging. We prepared GNRs with hypoxia-targeting nitroimidazole units (G-NI) on their surface. Biological experiments revealed that G-NI produced a strong photoacoustic signal in hypoxic tumor cells and tissues.

Identifiers

PMID35516361
PMCPMC9064429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.