Evidence map›Paper›PMID 35516338›Full record

ArticleRSC advances2019

One-pot detection of telomerase activity with high sensitivity and specificity

Honghong Wang, Hui Wang, Yuting Jia, Mai Zhang, Zhengping Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Honghong WangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China winscavin@ustb.edu.cn lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-8535-5358
Hui WangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China winscavin@ustb.edu.cn lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-5116-1977
Yuting JiaSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China winscavin@ustb.edu.cn lzpbd@ustb.edu.cn.
Mai ZhangSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China winscavin@ustb.edu.cn lzpbd@ustb.edu.cn.
Zhengping LiSchool of Chemistry and Biology Engineering, University of Science and Technology Beijing Beijing 100083 P. R. China winscavin@ustb.edu.cn lzpbd@ustb.edu.cn.ORCID https://orcid.org/0000-0002-7573-8822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human telomerase is a universal cancer biomarker and a promising anticancer therapeutic target. Sensitive and specific detection of telomerase activity is of great significance for cancer diagnosis and treatment. Up to now, many methods have been established to detect the activity of telomerase, but most of these methods require complex probe design and tedious experimental steps generally including telomere extension reaction, amplification of the extended products and signal detection. Herein, we propose a one-pot method to detect the telomerase activity

Identifiers

PMID35516338
PMCPMC9064132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.