Evidence map›Paper›PMID 35516274›Full record

ArticleRSC advances2020

A method to detect immunoreactions on the basis of current

Jagriti Gupta, Jyoti Bisht, Mini Agrawal, Jaydeep Bhattacharya, Prasenjit Sen, Ranjita Ghosh Moulick

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jagriti GuptaSchool of Biotechnology, Jawaharlal Nehru University New Delhi 110067 India.ORCID https://orcid.org/0000-0003-2517-6793
Jyoti BishtDepartment of Physics and Astronomy, NIT Rourkella Odissa 769008 India.
Mini AgrawalAmity Institute of Integrative Sciences and Health, Amity University Haryana, Amity Education Valley Haryana - 122413 India ranjita.ghoshmoulick@gmail.com.
Jaydeep BhattacharyaSchool of Biotechnology, Jawaharlal Nehru University New Delhi 110067 India.ORCID https://orcid.org/0000-0001-7268-0867
Prasenjit SenSchool of Physical Sciences, Jawaharlal Nehru University New Delhi 110067 India.
Ranjita Ghosh MoulickAmity Institute of Integrative Sciences and Health, Amity University Haryana, Amity Education Valley Haryana - 122413 India ranjita.ghoshmoulick@gmail.com.ORCID https://orcid.org/0000-0003-1890-8458
Jawaharlal Nehru University · INAmity University · AENational Institute of Technology Rourkela · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of novel infectious diseases is rising with time and is a major threat to the society. The recent outbreak of infectious coronavirus disease has made a huge impact in our lives. The massive outbreak of the disease revealed that there is room for development of new diagnostics tools and methods to screen huge numbers of samples in the shortest possible time. Our current work relates to an electronic diagnostic system and method that rapidly detects the presence of an antigen in solution. Our designed system is capable of separating the immunocomplex formation on the basis of the slope it produces in contrast to the controls, when oxidation peak current is plotted against the concentration of the reactant after electrochemistry measurement. In this system, antibody conjugated copper nanoparticles synthesized by the electroexplosion method has played the key role. The values of the slopes of copper nanoparticles (CuNPs) was found to be -3.7637, whereas those for CuNP conjugated Antibody and CuNPAntibodyAntigen were -2.3044 and -0.8332, respectively. Hence, the current method could become one of the easiest and fastest method for the electronic detection of an immune reaction and a good replacement for the time-consuming, label-based assays in multistep reaction.

Identifiers

PMID35516274
PMCPMC9058649
OpenAlexW3116291727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.