ArticleRSC advances2020
Luminescent chitosan/carbon dots as an effective nano-drug carrier for neurodegenerative diseases.
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 97 citations in OpenAlex.
- Plasma-Assisted and Green Routes to Silicon and Carbon Quantum Dots: A Critical Comparison of Synthesis-Structure-Property Relationships.Nanomaterials (Basel, Switzerland) · 2026Review
- Insights Into the Antibiofilm Activity of Carbon Quantum Dots Against a Panel of Different Microorganisms: A Review.MicrobiologyOpen · 2026Review
- Review
- Influence of the Ripeness Stages of the Precursors on the Optical Characteristics of Carbon Dots Obtained from Valencia Orange Peels (Nanomaterials (Basel, Switzerland) · 2026Article
- Luminescent heparin-functionalized carbon dots with potential applications in nanoparticle-protein interactions and cell imaging.Scientific reports · 2026Article
- Fluorescent Poly(vinyl alcohol) Composite Films Incorporating Doped Carbon Dots for Heavy Metal Detection in Smart Packaging Applications.ACS omega · 2026Article
- Nanotechnology in Parkinson's Disease: overcoming drug delivery challenges and enhancing therapeutic outcomes.Drug delivery and translational research · 2026Review
- Therapeutic and Diagnostic Implications of Carbon Dot: An Advancement in the Avenue towards Cancer, Diabetes and Neurodegenerative Disorders.Pharmaceutical nanotechnology · 2026Review
- Article
- Unveiling the molecular mechanism of acyclovir interaction with carbon dots: a DFT approach.Journal of molecular modeling · 2025Article
- Chitosan (Nano)formulations as Therapeutic Tools for Neurodegenerative Diseases: A Comprehensive Review.Polymers · 2025Review
- Sustainable Doped Carbon Dots as Antioxidant and Nanocarrier for Therapeutic Cargos.Journal of fluorescence · 2025Article
- Effect of temperature on the carbonization process of cationic carbon dots: a physicochemical andRSC advances · 2025Article
- Carbon Dots as a Fluorescent Nanosystem for Crossing the Blood-Brain Barrier with Plausible Application in Neurological Diseases.Pharmaceutics · 2025Article
- Carbon Nanodots-Based Polymer Nanocomposite: A Potential Drug Delivery Armament of Phytopharmaceuticals.Polymers · 2025Review
- Green Synthesis of Curcumin Loaded Carbon Dots as a Sustained Drug Delivery for Anticancer Therapy.Current pharmaceutical design · 2025Article
- Sustainable synthesis of carbon dots via bio-waste recycling for biomedical imaging.Smart medicine · 2024Article
- Efficacy and prognostic analysis of carbon nanotracers combined with the da Vinci robot in the treatment of esophageal cancer.World journal of clinical cases · 2024Article
- Emerging trends in CDs@hydrogels composites: from materials to applications.Mikrochimica acta · 2024Review
- Carbon Quantum Dots: Properties, Preparation, and Applications.Molecules (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Designing new materials for effective and targeted drug delivery is pivotal in biomedical research. Herein, we report on the development of a chitosan/carbon dot-based nanocomposite and investigate its efficacy as a carrier for the sustained release of dopamine drug. The carbon dots (CDs) were synthesized from the carbonization of chitosan and were further conjugated with chitosan (CS) to obtain a chitosan/carbon dot (CS/CD) matrix. Dopamine was later encapsulated in the matrix to form a dopamine@CS/CD nanocomposite. The cytotoxicity of IC-21 and SH-SY5Y cell lines was studied at various concentrations of the nanocomposite and the results demonstrate around 97% cell viability. The photoluminescence property revealed the characteristic property of the carbon dots. When excited at 510 nm an emission peak was observed at 550 nm which enables the use of carbon dots as a tracer for bioimaging. The HRTEM images and the D, G, and 2D bands of the Raman spectra confirm the successful synthesis of carbon dots and through DLS the particle size is estimated to be ∼3 nm. The release studies of the encapsulated drug from the composite were analyzed in an
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.