Evidence map›Paper›PMID 35516040›Full record

ArticleRSC advances2020

MIDA boronate allylation - synthesis of ibuprofen.

David Phillips, Glen Brodie, Sarah Memarzadeh, Gi Lum Tang, David J France

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David PhillipsSchool of Chemistry, University of Glasgow Glasgow G12 8QQ UK david.france@glasgow.ac.uk.
Glen BrodieSchool of Chemistry, University of Glasgow Glasgow G12 8QQ UK david.france@glasgow.ac.uk.
Sarah MemarzadehSchool of Chemistry, University of Glasgow Glasgow G12 8QQ UK david.france@glasgow.ac.uk.
Gi Lum TangSchool of Chemistry, University of Glasgow Glasgow G12 8QQ UK david.france@glasgow.ac.uk.
David J FranceSchool of Chemistry, University of Glasgow Glasgow G12 8QQ UK david.france@glasgow.ac.uk.ORCID https://orcid.org/0000-0002-5409-3316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MIDA boronates are among the most useful reagents for the Suzuki-Miyaura reaction. This chemistry typically generates new bonds between two aromatic rings, thereby restricting access to important areas of chemical space. Here we demonstrate the coupling of MIDA boronates to allylic electrophiles, including a new synthesis of the well-known COX inhibitor ibuprofen.

Identifiers

PMID35516040
PMCPMC9056333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.