Evidence map›Paper›PMID 35516013›Full record

ArticleRSC advances2020

A deep-red fluorescent molecular rotor based on donor-two-acceptor modular system for imaging mitochondrial viscosity.

Xiaoxi Yin, Yiping Cai, Songtao Cai, Xiaojie Jiao, Chang Liu, Song He, Xianshun Zeng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoxi YinTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Yiping CaiTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Songtao CaiTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Xiaojie JiaoTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Chang LiuTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Song HeTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.
Xianshun ZengTianjin Key Laboratory for Photoelectric Materials and Devices, Tianjin University of Technology Tianjin 300384 China hesong@tjut.edu.cn xshzeng@tjut.edu.cn +86-22-6021-6748.ORCID https://orcid.org/0000-0001-7761-0198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new donor-two-acceptor modular fluorescence rotor DpCy7 involving a phenolate donor unit and two benzothiazolium acceptor moieties was designed and synthesized. The DpCy7 underwent an internal charge transfer to form a Cy7-like longer conjugated system fluorochrome at a physiological pH. The probe exhibited a strong turn-on (8.5-fold) deep-red emission with a larger Stokes shift in glycerol aqueous solutions with restriction of rotation. Both the fluorescence intensity and fluorescence lifetime displayed the linear relationship of viscosity changes in the logarithmic plots. Furthermore, the HeLa cell imaging experiments of DpCy7 indicated that the rotor could be used to monitor the mitochondrial viscosity in living cells. This new type of deep-red fluorescence rotor provides a potential platform for determining viscosity at subcellular levels.

Identifiers

PMID35516013
PMCPMC9056405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.